The kinship matrix (IBS method) calculated with Tassel 575 and the population structure at K213 were included in the models as fixed factors. Quantile–quantile (Q–Q) plots were obtained by plotting the observed −log10(p values) against the expected -log10(p values) under the null ...
The human brain forms functional networks of correlated activity, which have been linked with both cognitive and clinical outcomes. However, the genetic variants affecting brain function are largely unknown. Here, we used resting-state functional magnetic resonance images from 47,276 individuals to disc...
Postmortem brain studies are potentially confounded by premortem and postmortem factors; thus, we statistically adjusted for the variation introduced by age, brain pH, postmortem interval, and refrigerator interval. We also carried out post hoc analyses within the disease groups for the effects of ...
While there are many factors to blame for wildfires, the following are the most common causes of wildfires, according to International Fire & Safety Journal.Lightning During periods of drought, lightning can cause wildfires by striking dry patches of vegetation....
Therefore, the sample size of adult terns in this study is small since we only collected deceased birds and, as a threatened species, terns cannot be sacrificed for scientific purposes. It is important to note that the bird carcasses were exposed to many factors between time of death and ...
Lipopolysaccharides (LPS), vesicles and proteins, polysaccharide capsules, phospholipases, proteases, outer membrane purines, biofilm, efflux pump, and iron absorption systems are the most important factors of resistance of this bacterium, which protect bacteria against biocides or drying on hospital ...
PAS1 domains are structural modules that can be found in proteins in all kingdoms of life (1, 2). The PAS module was first identified in theDrosophila clock protein PER and the basic helix-loop-helix containing transcription factors ARNT (aryl-hydrocarbon receptor nuclear translocator) in mammals...
Historical population dynamics and influencing factors inD. Delphis The estimation of the historical effective population size is intrinsically tied to our understanding of the species’ evolutionary history [147]. As it provides insights into the past population size of the species and how historical ...
Connie Bezzina, Richard Redon and colleagues show that common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disorder with high risk of sudden cardiac death. The newly discovered loci have a large cumulative effect on dise
of the opioid and dopamine systems in modulating both pain and pleasure. Understanding the mutually inhibitory effects that pain and reward processing have on each other, and the neural mechanisms that underpin such modulation, is important for alleviating unnecessary suffering and improving well-being....