2.5 M), (3) iron standards, (4) the sample of interest (either cell lysates or biological mice samples), and (5) absorbance measurements. “Labile iron measurements using the u-ferene assay” outlines the measurement of labile iron and “Total iron measurements using the u-ferene ...
neurons of FRDA patients [324], the skeletal muscle of individuals with ISCU myopathy [227], the precursors of red blood cells in a patient with SA caused by deficiency of GLRX5 [108], and in individuals affected by X-linked sideroblastic anemia and ataxia caused by mutations in ABCB7 [...
Therefore, abnormal gastric acid might be an unfavorable factor for intestinal iron absorption or even iron deficiency anemia in CAG patients. Figure 7. A schematic showing hepcidin involvement in CAG injury. CAG can increase IL-6 expression and then activate hepcidin via the JAK2/STAT3 signaling ...