- weight loss- iron deficiency anemia Crohn's disease - idiopathic inflammatory disorder- affects any part of digestive tract- strong association with nucelotide-binding oligomerization domains (CARD15/NOD2) mutations - skip lesions, cobblestone appearance- ulcerations = longitudinal & transverse ...
Persistence of goiter despite oral iodine supplementation in goitrous children with iron deficiency anemia in Cote d’Ivoire. Am. J. Clin. Nutr. 2000, 71, 88–93. [Google Scholar] [CrossRef] Hess, S.Y.; Zimmermann, M.B.; Adou, P.; Torresani, T.; Hurrell, R.F. Treatment of iron ...
Thalassemia, a chronic disease with chronic anemia, is caused by mutations in the β-globin gene, leading to reduced levels or complete deficiency of β-globin chain synthesis. Patients with β-thalassemia display variable clinical severity which ranges from asymptomatic features to severe transfusion-...
results in iron deficiency anemia, colon cancers or polyps in colon or rectum sinusoids capillaries that are located between the hepatocytes and receive venous and arterial blood from the hepatic artery and portal vein kupffer cells specific macrophages of the liver. they line the sinusoids and ...
Hemoglobin is a tetrameric protein, with two α and two β globin chains each, which are bound ionically, non-covalently to hydrophobic contact regions and the heme group, which consists of a porphyrin ring with a central iron atom for oxygen affinity. The heme group is located in a V-sh...
The condition is common in premature infants, debilitated children, and in other immu- nocompromised conditions, particularly the acquired immune deficiency syndrome (AIDS), but it is also seen in congenital immunodefi- ciency and in patients who are receiving chemo- therapy and corticosteroids. ...
iron accumulation stored as: 1. Ferritin (normal) 2. Hemosiderin (high levels of iron): yellow-brown pigment derived from hemoglobin. looks like big darkened area on skin hemosiderosis excess iron stored as hemosiderin caused by prolonged doses of iron and frequent transfusions/hemolysis ...
ANEMIA- iron deficiency anemia - most common - RBCS are small and low hemoglobin (pale)- iron is lost by desquamation of skin and intestinal cells ANEMIA - megaloblastic anemia - caused by deficiency of VIT B12 or FOLIC ACID- Vit B12 (cobalamin)º found in MEAT, EGGS, and dairy produ...