Iron-deficiency anaemia and delay in the diagnosis of colorectal cancer . Colorectal Dis 2003 ; 5: 145-148.P. L. Acher, T. Al-Mishlab, M. Rahman, and T. Bates, "Iron- deficiency anaemia and delay in the diagnosis of colorectal cancer," Colorectal Disease, vol. 5, no. 2, pp. ...
We would like to express our sympathy to the family and to acknowledge the tragedy of the circumstances in regard to the death of their 29-year-old family member from metastatic colon cancer. To summarise, the woman presented at the age of 22 years with severe iron deficiency anaemia (IDA)...
Iron deficiency (ID) is the most common nutritional disorder worldwide. It is often observed in patients with chronic diseases, such as heart failure (HF), chronic kidney disease (CKD), inflammatory bowel disease (IBD) and cancer. ID is associated with poor clinical outcome, including poor per...
Many types of cancer cells reprogramme iron metabolism in ways that result in net iron influx. They upregulate proteins that are involved in iron uptake, such as transferrin receptor 1 (TFR1), STEAP proteins and lipocalin 2 (LCN2), and decrease the expression of iron efflux proteins, such a...
et al. Ectopic expression of neutrophil gelatinase-associated lipocalin suppresses the invasion and liver metastasis of colon cancer cells. Int. J. Cancer 118, 2490–2497 (2006). Article CAS PubMed Google Scholar Sun, Y. et al. NGAL expression is elevated in both colorectal adenoma-carcinoma ...
Grown-ups with intestinal bleeding: adults who suffer from intestinal problems that cause bleeding have a higher risk of iron deficiency anaemia. Causes may include ulcers, colon cancer and taking medications that can result in bleeding, such as non-steroidal anti-inflammatory medication. ...
Patients requiring elective colorectal cancer surgery have a high prevalence of anemia and iron deficiency. Intravenous iron therapy, with or without recombinant erythropoietin (EPO), may play an important role in the correction of perioperative anemia and facilitate preoperative autologous donation, thus ...
In addition, unabsorbed intestinal iron has been suggested to increase the risk of colon cancer. Iron supplementation or fortification in functional foods should be avoided and discouraged until the risks of iron overload have been more clearly determined, since in the general population iron over...
The first step is to find out what is causing the iron deficiency. Men and postmenopausal women may need to have their stomach and intestines examined to make sure that they do not have any hidden bleeding. This is especially important in older adults because colon cancer can cause iron defic...
We examined associations among colon cancer incidence and dietary intake of heme iron, a possible prooxidant, zinc, a possible antioxidant, and alcohol, a disruptor of iron homeostasis. During 15 years of follow-up, 34 708 postmenopausal women, aged 55-69 years at baseline who completed a food...