IRG1-IN-1 是衣康酸衍生物。IRG1-IN-1 可以抑制免疫反应基因 1 (IRG1) 的活性。IRG1-IN-1 可用于癌症、炎症和自身免疫性疾病的研究。此产品仅用于科学研究,我们不为任何个人用途提供产品和服务库存: 现货 可选规格 包装 10mg 25mg 50mg 100mg 数量 - + 确认 取消 ￥ 2180-12820 ...
IRG1-IN-1 是衣康酸衍生物。IRG1-IN-1 可以抑制免疫反应基因 1 (IRG1) 的活性。IRG1-IN-1 可用于癌症、炎症和自身免疫性疾病的研究。 详细介绍 产品活性:IRG1-IN-1 是衣康酸衍生物。IRG1-IN-1 可以抑制免疫反应基因 1 (IRG1) 的活性。IRG1-IN-1 可用于癌症、炎症和自身免疫性疾病的研究。
Frontiers in Immunology:杨菲/李纤团队揭示IRG1/衣康酸对神经性疼痛的镇痛作用及相关分子机制 2022年10月,首都医科大学等单位的相关研究人员在《Frontiers in Immunology》(IF: 8.8)上发表了题为“IRG1/itaconate increases IL-10 release to alleviate mechanical and thermal hypersensitivity in mice after nerve in...
Aconitate decarboxylase 1 (ACOD1, also known as immunoresponsive gene 1 [IRG1]) is a key regulator of immunometabolism during infection and inflammation.[20], [21], [22] It was first discovered in 1992 as a lipopolysaccharide (LPS)-inducible gene in murine macrophages.[23] Later, metabolo...
immunohistochemistry: 1:200-1:500 免疫原序列RPADRQEENKAGLLDLPDASVNGWSSDEEKAGGLDDEEEAELVPSEVLMHQAIHTI UniProt登记号Q13488 运输wet ice 储存温度−20℃ Gene Informationhuman ... TCIRG1(10312) 安全信息 储存分类代码10 - Combustible liquids
Monoclonal Anti-TCIRG1 antibody produced in mouse OC116 Vph1 ATP6V0A3 OPTB1 OC-116kDa ATP6N1C Atp6i TIRC7 Stv1 产品性质 Quality Level【质量水平】 100 biological source【生物来源】 mouse conjugate【偶联物】 unconjugated antibody form【抗体形式】 ascites fluid antibody product type primary anti...
IRG1 deficiency exacerbates ovariectomy‐induced osteoporosis.Itaconate ameliorates ovariectomy‐induced osteoporosis in IRG1 KO mice.IRG1 deficiency enhances RANKL-induced osteoclastogenesis in BMMs.Itaconate prevents RANKL-induced osteoclastogenesis in IRG1 KO BMMs.IRG1/itaconate protects against osteoporosis b...
ACOD1 (also known as IRG1) has emerged as a regulator of immunometabolism that operates by producing metabolite itaconate. Here, we report a key role of STING1 (also known as STING and TMEM173) in mediating ACOD1 expression in myeloid cells in response to toll-like receptor (TLR) signali...
Mutations in TCIRG1 are responsible for more than 50% of ARO-affected individuals[6], demon- strating the crucial role of the V-ATPase in osteoclast func- tion. Despite rapid development in the understanding of the pathogenesis of osteopetrotic conditions, the genetic basis of approximately 30...
However, activation of this pathway in ZIKV-infected neurons did not induce cell death. Rather, RIPK signaling restricted viral replication by altering cellular metabolism via upregulation of the enzyme IRG1 and production of the metabolite itaconate. Itaconate inhibited the activity of succinate ...