The optimum route of administration is an importance clinical issue not only for chemical drug, but also for stem cytotherapy. The accessibility of the therapeutic cells to their expectable target site is strongly dependent on the route of administration used. Therefore, the MSCs delivery should be...
Uncertainty over the future of the GCC patent and how or whether the regional patenting route will continue to exist Most sector-specific rights are missing Ecuador Ranking: 50/55 The strength of a nation’s IP framework compared to others, with 1 being strongest and 55 the weakest. ...
The latter route would require the USPTO to rethink their existing framework of determining inventorship by who conceived the invention. Takeaway The degree of human involvement will likely determine whether an AI work can be protected by copyright, and potentially patents. Before incorporating this ...
the definition of the quality target product profile (QTPP) as it relates to quality, safety and efficacy, considering, bo nimûne, the route of administration, dosage form, bioavailability, strength and stability; identification of the potential critical quality attributes (CQAs) of the FPP...
In 2021, Hong Kong’s IP Department granted the first standard patent under the new original grant patent (OGP) system that creates a direct route for innovators to seek standard patent protection in the city. This is considered a milestone in the development of Hong Kong’s patent system....
The subsequent potential enlargement of disease spectrum to chronic disorders in the same setting, as well as in NDD, posed the challenge of gaining a more suitable route of administration, such as the oral route, for prolonged administration. By February 2022, Fasudil is investigated in ...
Therefore, AAV-NRIP may not only improve SOD1 G93A mice but also potentially alleviate other types of ALS. Future efforts will focus on optimizing the injection route, timing of therapeutic administration, and employing tissue-specific promoters to drive NRIP gene expression, aiming to enhance ...
Pharmaceutical compositions will generally be tailored to the specific intended route of administration.As used herein, a “carrier” refers to a compound that facilitates the incorporation of a compound into cells or tissues. For example, without limitation, dimethyl sulfoxide (DMSO) is a commonly ...
weight, and general health of the patient, the tolerance of the patient to the active agent, the route of administration, pharmacological considerations such as the activity, efficacy, pharmacokinetics and toxicology profiles of the compound and any secondary agents being administered, and the like. ...
IP route promotes more MSCs migration to inflamed colon The number of therapeutic cells that can migrate and colonize at the injury site is a decisive prerequisite for the success of cytotherapy. In order to compare the difference of MSCs colonization among the three delivery routes, a nontoxic ...