Dain, The in vitro glycation of human serum albumin in the presence of Zn(II), J. Inorg. Biochem. 105 (2011) 1548-1554.Seneviratne C, Dombi GW, Liu W, Dain JA (2011) The in vitro glycation of human serum albumin in the presence of Zn(II). J Inorg Biochem 105:1548-1554. doi:...
These early products endure slow and complex rearrangements to create advanced glycation end-products (AGEs) that are involved in diabetic complications. Here, the biophysical characteristics of in vitro glycated human serum albumin (HSA) are compared to those of HSA glycated in vivo. The changes ...
Glycated human serum albumin (HSA) is known to be involved in the pathogenesis of several diseases, and we have therefore investigated possible alterations in HSA on glycation. HSA was incubated for 5 and 20 weeks independently with constant glucose concentration at 37°C under aerobic conditions....
The studies allowed us to indicate the structural alterations of human serum albumin as a result of fructose glycation. Changes in binding parameters, such as association ( K a ) or Stern-Volmer ( K S V ) constants suggest that glycation increases the affinity of TB and LOS towards albumin ...
Diabetes mellitus is a metabolic disorder resulting in decreased number of pump units on the erythrocyte membrane, altered lipid–protein interactions, enzyme glycation and peroxidation which account for many complications [1]. Human erythrocytes are continuously exposed to glucose in plasma during their ...
Glycation of human serum albumin by acylglucuronides of nonsteroidal anti-inflammatory drugs of the series of phenylpropionates The covalent binding to human serum albumin (HSA), of acylglucuronides from carboxylic nonsteroidal anti-inflammatory drugs (NSAIDs) was investigated. The ... H Georges,I...
[70]. A hypothesis posits an increase in oxidative stress among individuals with diabetes. The action of oxygen free radicals may trigger lipid peroxidation, setting in motion the glycation of proteins. Consequently, this process can deactivate enzymes, modify collagen structure and function, and ...
Thus, the goal of the present study was to compare the in vitro formation of glycated albumin in chicken serum albumin (CSA) and bovine serum albumin (BSA) exposed to a range of glucose concentrations over a 16-week period. The level of glycation for CSA and BSA was quantified using ...
The analysis of the antioxidant activity by discolouration of 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) and by inhibition of the glycation of bovine serum albumin has put in evidence that the best results were obtained in the fractions involved flavanols and procyanidins from the...
Regarding shrimp allergy, TM has been modified by glycation (GTM) and combined with Al(OH)3 to form hypoallergenic complex and be used in AIT. This hypoallergenic complex has been able to induce desensitization in allergic reactions in shrimp allergic patients [96,97]. The glycation in the ...