Recently, a 22 kDa natural inhibitor to IL-1 called interleukin-1 receptor antagonist ( IL-1ra ) has been described in human fluids, which specifically binds IL-1伪 or IL-1尾 receptors. In this study, we found that experimental granuloma induced by subcutaneous injections (0.2 ml) of ...
Rothwell, Interleukin-1 receptor antagonist in- hibits neuronal damage caused by fluid percussion injury in the rat, Brain Res. 671 Z1995. 261-266.Toulmond S & Rothwell NJ. (1995). "Interleukin-1 receptor antagonist inhibits neuronal damage caused by fluid percussion injury in the rat". ...
Pancreatic ductal adenocarcinoma (PDA) is a pernicious disease characterized by an immunosuppressive milieu that is unresponsive to current immunotherapies. Interleukin-1 receptor antagonist (IL-1Ra) is a natural anti-inflammatory cytokine; however, its
nervous system; DAMP, damage-associated molecular pattern; IL- interleukin; IL-1ra, IL-1 receptor antagonist; JNK, c-Jun N-terminal kinase; NGF, nerve growth factor; NFκB, nuclear factor kappa light-chain-enhancer of activated B cells; NLR, nucleotide-binding oligomerization domain-like recepto...
Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor Nature, 343 (1990), p. 336 View in ScopusGoogle Scholar 19 Carter DB, Deibel MR, Dunn CJ, Tomich C-SC, Laborde AL, Slightom JL, Berger AE, Bienkowski MJ, Sun FF, McEwan RN, Harris PKW, Yem AW, Waszak GA...
In this study, we investigated the ability of human recombinant IL-1 receptor antagonist (IL-1ra) to inhibit IL-1-induced cytokine production in human peripheral blood mononuclear cells (PBMC) and isolated monocytes. IL-1ra alone at concentrations as high as 1 microgram/mL did not induce IL-...
Recombinant Mouse Interleukin-1 receptor antagonist protein(Il1rn) (Active)的详细介绍 产品类型: Interleukin 产品名称: uniprot号: 规格: ￥620 图像: 基因名称: Il1rn 别名: IL-1RN, IRAP, IL1 inhibitor 种属: Mus musculus (Mouse) 蛋白描述: ...
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Background and Purpose—The proinflammatory cytokine IL-1 (interleukin-1) has a deleterious role in cerebral ischemia, which is attenuated by IL-1 receptor antagonist (IL-1Ra). IL-1 induces peripheral inflammatory mediators, such as interleukin-6, which are associated with worse prognosis after is...
Pancreatic ductal adenocarcinoma (PDA) is a pernicious disease characterized by an immunosuppressive milieu that is unresponsive to current immunotherapies. Interleukin-1 receptor antagonist (IL-1Ra) is a natural anti-inflammatory cytokine; however, its