Interleukin-1beta:a common thread between inflammation,pain and opioid tolerance opioidpaindosageChronic pain is a major health issue in our society that clearly impacts quality of life.Thirty to forty percent of the population in the United States suffer from chronic pain and its total cost have...
A high level of Interleukin-1beta (IL1B), a key mediator of inflammation, is expressed in the brain, particularly in thehippocampus, which plays a pivotal role in memory and mood regulation. In the brain,IL1Bexerts a myriad of effects such as neuronal proliferation, differentiation, apoptosis...
Interleukin-1: a pos- sible mediator of lung inflammation and airway hyperreactivity. Pharmacol Res 1991; 24:385-93.Hernandez A,Omini C,Daffonchio L.Interleukin-1 beta : a possible mediator of lung inflammation and airway hyperreactivity. Pharmacological Research . 1991...
Interleukin-1beta regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability. PLoS One 8, e53626 (2013). Article CAS PubMed PubMed Central Google Scholar Howard, C. et al. Safety and tolerability of canakinumab, an IL-1beta inhibitor...
白细胞介素1β(IL-1β)也称为白细胞热原,白细胞内源性介质,单核细胞因子,淋巴细胞活化因子等名称,是人中由IL1B 基因编码的细胞因子蛋白。白介素1(IL-1)有两个基因:IL-1 alpha和IL-1 beta(该基因)。IL-1β前体被胞浆胱天蛋白酶1(白介素1β转化酶)裂解形成成熟的IL-1β。
cytokine levels within the GCF reflect the microbial activation of the host’s immune response. IL-1β has been established as a robust GCF biomarker for a hyper-inflammatory phenotype, as well as severe clinical inflammation, bone loss and periodontal disease progression6,7,8,9,10. It is a...
systemic inflammation which is etiologically linked to the pathogenesis of obesity related diseases such as cardiovascular disease and type 2 diabetes. While the obesity epidemic has fueled considerable interest in these obesity-related inflammatory diseases, surprisingly little research is currently focused ...
The meaning of INTERLEUKIN-1 is an interleukin produced especially by monocytes and macrophages that regulates immune responses by activating lymphocytes and mediates other biological processes (such as the onset of fever) usually associated with infecti
Summary Inflammation is part of the non-specific immune response that occurs in reaction to any type of bodily injury. In some disorders, the inflammatory ... L Ferrero-Miliani,OH Nielsen,PS Andersen,... - 《Clinical & Experimental Immunology》 被引量: 996发表: 2010年 Interleukin-1beta down...
aThe blockade of interleukin-1 with anakinra improved glycemia and beta-cell secretory function and reduced markers of systemic inflammation. ( 正在翻译,请等待... [translate] a场景 正在翻译,请等待... [translate] aThe expression of interleukin-1–receptor antagonist is reduced in pancreatic islets ...