Lynch MA.Interleukin-1 beta exerts a myriad of effects in the brain and in particular in the hippocampus: analysis of some of these actions. Vitamins and Hormones . 2002LYNCH MA.Interleukin-1beta exerts a myriad of effects in the brain and in particular in the hippocampus:analysis of some ...
Processing of IL-1β to its active form was inhibited by blocking the intracellular actions of caspase 1 with a specific antagonist (N-Acetyl-TRP-GLU-His-Asp-AL). As a result, the total number of cells (Fig. 7c), the number of activated microglia expressing P2X7R (Fig. 7d), and the...
Evidence also suggests that, through its stimulating effect on the 11-beta hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme which converts inactive glucocorticoids into their active form, IL-1β may indirectly increase local glucocorticoid activity [131,132]. This could consequentially serve ben...
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Processing of IL-1β to its active form was inhibited by blocking the intracellular actions of caspase 1 with a specific antagonist (N-Acetyl-TRP-GLU-His-Asp-AL). As a result, the total number of cells (Fig. 7c), the number of activated microglia expressing P2X7R (Fig. 7d), and the...
Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Interleukin 1 Beta (IL1b) were tested 20 times on one plate, respectively. Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Interleukin 1 Beta (IL1b)...
Many physiological actions and biological activities of IL-1 have been identified. IL-I biological activity is often determined by assaying for stimulation of thymocyte proliferation or by measuring interleukin-2 (IL-2) biological activity. IL-I activities include stimulation of B-lymphocyte maturation...
Interleukin-1β (IL-1β) has been shown by several investigators to be a stimulator of adrenal glucocorticoid production in vivo. However, little evidence exists for direct actions of IL-1β on the adrenal gland. We sought to elucidate the direct effects, if any, of IL-1β on human fetal...
Objective To investigate the effect(s)of interleukin-1β(IL-1β)on the activity of human growth hormone(hGH)gene promoter in rat pituitary GH3 cells and the molecular mechanism. Methods The method of luciferase reporter gene was used. We firstly established stable GH3 cell line which contains ...
Inhibitory actions of interleukin-1β on steroidogenesis in primary cultures of neonatal rat testicular cells Fauser BC, Galway AB, Hsueh AH 1989 Inhibitory actions of interleukin-1 beta on steroidogenesis in primary cultures of neonatal rat testicular cells. Acta Endocrinol (Copenh) 120:401- 408Faus...