This chapter focuses on interferon-gamma (IFN-γ). The single-copy hIFN-γ gene, situated on chromosome 12 in the p12.05-qter region, contains three introns. The production of IFN-γ is limited to T cells and natural killer (NK) cells. T cells are stimulated to produce IFN-γ either ...
9.7.2Gamma interferon assay Interferon-γ (IFN-γ) is a significant cytokine that plays a key role inhost immune responses. In the initial phase of infection withB.abortus, an increased number of CD4+cells as well as expression of IFN-γ was observed (Dorneles et al., 2015;Zhu, Tang, ...
Autocrine stimulation of interleukin 1 in human adherent synovial lining cells: Down regulation by interferon gamma - ScienceDirect 来自 Semantic Scholar 喜欢 0 阅读量: 24 作者: Nathalie,Temime,and,Arlette,Joliviere,and,Danièle,Lando,and,Luc 展开 摘要: Interleukin 1 (IL-1) exerts ...
Interferon gamma expressionThe present invention is directed to methods of treating or preventing angiomyolipomas by administering interferon gamma. It also encompasses methods for assessing the risk of a patient developing angiomyolipomas based upon interferon gamma expression.Dabora, S. L...
Interferon GammaSoluble Interleukin-2 ReceptorTuberculosisBackground: pleural TB is a diagnostic challenge because of its nonspecific clinical manifestation. The efficiency of conventional laboratory method and the reliance on pleural biopsy have motivated the evaluation of alternative diagnostic strategies. The...
Normal human keratinocytes grown in MCDB 153 plus bovine pituitary extract and treated with recombinant gamma interferon (rIFN gamma) express HLA-DR, DP and DQ antigens. The expression of these class II Major Histocompatibility Complex antigens is time dependent: DR and DP appear before DQ. The...
Baron P, Villalba M, Ferrari D, Rossi F: Activation of microglial cells by beta-amyloid protein and interferon-gammaMeda, LCassatella, M. ASzendrei, G. IOtvos, LBaron, PVillalba, MRossi, FOtvos LSzendrel, Get al
Adult-onset immunodeficiency syndrome is characterized by the presence of anti-interferon-gamma (IFN-γ) autoantibody and the distribution of infections. Here, we describe Salmonella enterica bacteremia in a Thai woman who also had anti-IFN-γ autoantibody. The patient was also suffering from Salmone...
Access through your organization Check access to the full text by signing in through your organization. Access through your organization References (4) GF Black et al. BCG-induced increase in interferon-gamma response to mycobacterial antigens and efficacy of BCG vaccination in Malawi and the UK...
In Year 2, we planned to determine the presence of subtype of prostate cancer expressing high levels of IFN(gamma)R2 and Bax which is expected to be an ideal target subtype treated by IFN(gamma)R2 inhibiting strategy. We also planned to determine the effectiveness of IFN(gamma)R2 inhibition...