Some interferons are modified versions of the naturally occurring material and are prepared using recombinant DNA technology. Interferon is sometimes abbreviated as "IFN" and shall be so abbreviated in this application. Examples of interferons include, e.g. IFN-alpha-2A recombinant ("ROFERON®" A...
Another important antagonism is between type I IFNs and interleukin-1. This antagonism was recently shown to be important inM. tuberculosisinfection and to be mediated by eicosanoids, in particular prostaglandin E2. Thus, type I IFNs are part of a complex cross-regulatory network, which le...