In epithelial cancers, the epidermal growth factor receptor (EGFR) and integrin α6β4 are frequently overexpressed and found to synergistically activate intracellular signaling pathways that promote cell proliferation and migration. In cancer cells, the β4 subunit is phosphorylated at tyrosine residues ...
were probed with mAbs directed against β1 integrin subunit, ECL, and GAPDH.eImmunofluorescence of control andB4galt1−/−mouse BM sections stained with the antibody 9EG7 directed against activated β1 integrin subunit (red) and DAPI (blue).fQuantification of red fluorescence intensity in contr...
The monoclonal antibody natalizumab targets the α4 subunit of α4β1 and α4β7 integrins, implicated in the entry of lymphocytes in the central nervous system (CNS) and the gut mucosa, respectively. These integrins are involved in the pathogenesis of multiple sclerosis (MS) and inflammatory ...
Fluorescence-activated cell sorter analysis and immunoprecipitation with monoclonal antibodies demonstrated that normal dermal fibroblasts express the α4-subunit on the cell surface, primarily in association with the β1-subunit. Cell-attachment assays demonstrated that normal human fibroblasts can attach ...
中文名称: 整合素β2/Integrin β2抗体CD18图片 英文名称:CD18 别名:Integrin beta 2; 95 subunit beta; CD 18; Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor); Cell surface ad
英文名称: Integrin beta 1/CD29 中文名称: 整合素β1/Integrin β1抗体 别名:Integrin beta 1; Integrin beta-1; beta 1 subunit; CD 29; CD-29; CD29; CD29 antigen; Fibrinogen Receptor beta subunit; Fibronectin receptor subunit beta; Fibronectin receptor, beta subunit; FNRB; GPIIA; integrin bet...
A minor portion of type II expressed the alpha 4 (CD49d) subunit of the beta 1-integrins, and the alpha-v (CD51) subunit of the receptor. CD11a, CD11b, CD11c, , CD49b, and CD49f failed to demonstrate any immunostaining with type II . In conclusion, the observation of the ...
抗体名:Integrin alpha 5 beta 6; CD51; Integrin alpha-V light chain; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); Integrin, alpha V; Integrin, beta 6; ITAV_HUMAN; ITGAV; ITGB6; Vitronectin receptor subunit alpha.靶点:详见说明书 ...
抗体名:Alpha 5 beta 1; CD49 antigen-like family member E; CD49e; ECMRVI; Fibronectin Receptor alpha; Fibronectin receptor alpha subunit; Fibronectin receptor, alpha subunit; FNR; FNRA; gpIc/IIa; Integrin alpha 5 (fibronectin receptor alpha); Integrin alpha F; Integrin alpha-5; Integrin alp...
Because of the similar inhibitory effects of apocynin and obtustatin on ROS production, we investigated the translocation of the cytosolic subunit p47phox towards cell membrane, a key event required for NOX2 complex activation. When p47phox interacts with the NOX2 membrane subunit, NOX2 becomes a...