Integrin beta-like 1 overexpression stimulates invasiveness of ovarian cancer cells in vitrogrowth was assessed by inoculating cancer cells into the back of BALB/c nude mice. TBOPP, a selective inhibitor of DOCK1 that binds to the catalytic domain of DOCK1 and blocks its GEF activity, was ...
ILK (beta1-integrin-linked protein kinase) is a recently identified 59-kDa serine/threonine protein kinase that interacts with the cytoplasmic domain of the beta1-integrin containing four ankyrin-like repeats. We have developed a polyclonal antibody against ILK and explored the ILK immunoreactivity in...
Description Integrin beta 1 rabbit polyclonal antibody Protein full name Integrin beta-1 Synonyms Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29, ITGB1, FNRB, MDF2, MSK12 Immunogen Recombinant protein corresponding to Mouse Integrin beta 1 ...
Shank-interacting protein-like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells. J. Clin. Invest. 120, 2094–2108 (2010). Article CAS Google Scholar Landgraf, K. et al. Sipl1 and Rbck1 are novel Eya1-binding proteins with a role in craniofacial development. Mol. Cell....
In summary, the protein ICln directly binds the highly conserved (1020)KVGFFKR(1026) amino acids of the intracellular domain of the integrin αIIb via the (61)ISLHA(65) amino acid motif lying in the β4 - β5 loop and β5 sheet of its pleckstrin-homology-like N-terminal portion. The...
1 mg/mL 纯化类型 Protein G 保存液 PBS 内含物 no preservative 保存条件 -20° C, Avoid Freeze/Thaw Cycles 运输条件 Ambient (domestic); Wet ice (international) RRID AB_2745151 产品详细信息 This antibody recognizes murine CD51, approximately a 140 kDa alpha subunit of the vitronectin receptor, ...
Integrin VLA 4 subunit beta; ITGB;Anti-Integrin beta 1抗体ITGB1; MDF2; MSK12; Very Late Activation Protein beta Polypeptide; VLAB; VLAbeta; Glycoprotein IIa; GP IIa; Integrin VLA 4 subunit beta; integrin VLA-4 beta subunit; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen...
Integrin β1 deletion/downregulation decreased the expression of ACE2 in mouse renal epithelial cells, normal renal epithelial cells, and renal cancer cells. Furthermore, a pharmacological integrin α2β1 inhibitor decreased ACE2 expression and the internalization of SARS-CoV-2 spike protein in ...
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At first, we used synaptonemal complex protein 1 (Sycp1)-Cre and integrin subunit beta1 (Itgb1) floxed gene mice mating to generate sperm conditional knockout (KO) mouse, but this mouse did not show good excision efficiency at the point where males reproduced normally, with either wild-type...