Identifying insulin resistance offers significant—and often untapped—clinical value and can help healthcare providers and their patients take action with diet and lifestyle choices to avoid or change the progression to prediabetes and diabetes. Today
http://www.nutritionj.com/content/10/1/44 RESEARCH Open Access Flaxseed supplementation improved insulin resistance in obese glucose intolerant people: a randomized crossover design Yeong Rhee* and Ardith Brunt Abstract Background: Obesity leads to an increase in inflammation and insulin resistance. ...
Studies suggesting that combined therapy may be beneficial have appeared in the last few years, but this treatment option has faced considerable resistance. Traditionalists say that if insulin works well enouogh, why consider any other approach? Insulin, after...
The STAM™ model represents a previously well-described NASH mouse model where STZ-induced insulin resistance is used to accelerate the transition from fatty liver to NASH with HFD feeding. The 2-day-old pups of C57Bl/6J mice are given STZ, which reliably destroys 60% of β cells, as ...
Bot Stud (2021) 62:7 https://doi.org/10.1186/s40529-021-00315-8 ORIGINAL ARTICLE Open Access Extract of white sweet potato tuber against TNF‑α‑induced insulin resistance by activating the PI3K/Akt pathway in C2C12 myotubes Lie‑Fen Shyur1†, Viola Varga2,3†, ...
T-test was used to compare the mean values between two groups. Statistical analyses were performed using Excel. A P-value less than 0.05 was considered statistically significant. 3. Results and discussion 3.1. Characteristics of HFD-induced insulin resistance To build the mouse model of insulin re...
Dietary insulin load and insulin index are associated with the risk of insulin resistance: a prospective approach in tehran lipid and glucose study. J Diabetes Metab Disord. 2015;15:23. https://doi.org/10.1186/s40200-016-0247-5. 16. Sadeghi O, Hasani H, ...
Given the role of TonEBP in various inflammatory diseases, our long-term goal is to determine the function of TonEBP in adipose tissue expansion and insulin resistance. We began the quest by examining the role of TonEBP in adipogenesis and adipocyte inflammation. Here we report that TonEBP sup...
There was mild insulin resistance as assessed by an insulin tolerance test and small changes in insulin signaling to the anabolic intermediate Akt/PKB in the livers of the CerS2−/+ mice on the high-fat diet (Figures S1H and S1I). Moreover, liver cells from the CerS2−/+ mice on ...
"Insulin Resistance and Noninsulin-Dependent Diabetes Mellitus: Which Horse Is Pulling the Cart?", W. Timothy Garvey, Diabetes/Metabolism Reviews, 5(8):727-742 (1989). J.A. Maclaren et al., "The Preparation of Reduced and S-Alkylated Wool Keratins Using Tri-n-Butylphosphine," Aust. J....