Kim, Relationship between insulin resistance and amino acids in women and men. Physiol. Rep. 3, e12392 (2015)Seibert, R., F. Abbasi, F. M. Hantash, M. P. Caulfield, G. Reaven, and S. H. Kim. 2015. Relationship between insulin resistance and amino acids in women and men. Physiol...
Haploinsufficiency for ceramide synthase 2 (CerS2), the dominant isoform in the liver that preferentially makes very-long-chain (C22/C24/C24:1) ceramides, led to compensatory increases in long-chain C16-ceramides and conferred susceptibility to diet-induced steatohepatitis and insulin resistance. ...
Insulin resistance (IR) is linked to an atherogenic dyslipidemia and an increased risk of ASCVD. Apolipoprotein A1 (ApoA1)-associated lipoproteins exert varying anti-atherogenic functions and have a large diverse proteome. It is, however, unknown whether IR contributes to atherogenic perturbations in ...
Patients with NAFLD are characterized by insulin resistance (IR) and hyperinsulinism. However, prior studies have been unable to predict NAFLD based on IR measurements. The aim of this study was to explore the application of a newly validated measurement of intact insulin by mass s...
insulin resistanceobesityFasting intact insulin concentrations can predict metabolic dysfunction–associated steatotic liver disease (MASLD) in adults without diabetes; however, research in youth is limited. We sought to determine whether fasting intact insulin, measured by liquid chromatography-tandem mass ...
Associations between specific glucose-insulin biomarkers and CVD have been inconsistent.#Hypothesis:We hypothesized that higher insulin, C-peptide, insulin resistance score (IRS), and HbA1c are associated with incident CVD and coronary heart disease (CHD) events and that both vitamin D and omega-3...
A patient who shows signs of discomfort or resistance to learning how to utilize the device may not be a good fit. Some patients may benefit more from MDI than pump manipulation due to physical disabilities. When it comes to managing their diabetes and insulin needs, a patient’s intellectual...