Atzmon, N. Barzilai, The paradox of the insulin/IGF-1 signaling pathway in longevity. Mech. Ageing Dev. 125, 397-403 (2004).Rincon M, Muzumdar R, Atzmon G, Barzilai N (2004) The paradox of the insulin/IGF-1 signaling pathway in longevity. Mech Ageing Dev 125: 397- 403....
Insulin/IGF-1 Signaling Pathway Antibody Sampler Kit(1)结合特异性抗原:抗体与其他免疫球蛋白分子区别,就在于抗体能与相应抗原发生特异性结合,在体内导致生理或病理效应;在体外产生各种直接或间接的可见的抗原抗体结合反应。抗体是靠其分子上的特殊的结合部位与抗原结合的。
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1) insulin/IGF signal pathway 胰岛素/类胰岛素途径2) Insulin Pathway 胰岛素途径3) insulin-mimetic 类胰岛素 1. This review focuses on the signaling pathways mediating the insulin-mimetic and anticancer effects of vanadium compounds, as well as the correlationship between them. 本文对近年来关于钒...
Insulin-like Growth Factors and Receptors: IGF1R, IGF2, IGFBP1.SH3/SH2 Adaptor Protein: CBL, GAB1, GRB2, IRS4, NCK1.Other Genes Associated with Insulin Receptor Proteins: CAP1, DOK1, DOK2, DOK3, FRS2, FRS3, INSR, PDPK1, PPP1CA, PTPN1, PTPRF, SHC1. PI-3Kinase Pathway: Comp...
The C. elegans insulin/IGF-1 signaling (IIS) pathway connects nutrient levels to metabolism, growth, development, longevity, and behavior. This fundamental pathway is regulated by insulin-like peptide ligands that bind to the insulin/IGF-1 transmembrane receptor (IGFR) ortholog DAF-2. DAF-2/IGFR...
An accumulating body of evidence suggests the involvement of an evolutionary conserved insulin/insulin-like growth factor-1 (IGF-1) signaling (IIS) pathway in the regulation of the life and health span in nematodes, flies, rodents, and humans. We studied the association between insulin/IGF-1 si...
Given the cross-talk between the insulin and IGF signaling pathways, the aim of this study was to examine the hypothesis that the anti-proliferative actions of metformin in uterine serous carcinoma (USC) are potentially mediated via suppression of the IGF-I receptor (IGF-IR) pathway. Our ...
AIM: To address the possibility that insulin-like growth factor (IGF)-Ⅱ is a growth factor and its signaling pathway so as to develop a molecular therapy for hepatoblastoma.METHODS: Huh-6 and HepG2, human hepatoblastoma cell lines, were used. IGF-Ⅱ was added to the medium deprived of ...