The second aim of this study was to determine the effect of a 4-fold rise in head insulin on HGP during peripheral hyperinsulinemia and hepatic insulin deficiency. Sensitivity of the liver was not enhanced by increased insulin delivery to the head. Thus, this study demonstrates that the direct...
Neural sensing of insulin levels appears to participate in control of hepatic glucose production in rodents, but a role for brain insulin sensing has not been documented in dogs or humans. The primary effect of insulin on the liver is its direct action.关键词:...
Objective To reproduce a liver injury model in hyperglycemic rats, and investigate the effect of intensive insulin therapy on the liver. Methods Streptozotocin(STZ) and D-gal were injected to reproduce hyperglycemic liver injury model in rats. These rats were divided into intensive insulin group(with...
20. These results indicate that the effect of insulin on c-fos expression may be one of the mechanisms of neuroprotection of insulin. 胰岛素促进缺血脑组织c-fos基因表达,可能是其神经保护作用机制之一。 insulin 词典解释 1.胰岛素 Insulin is a substance that most people produce naturally in their bod...
insulin- hormone secreted by the isles of Langerhans in the pancreas; regulates storage of glycogen in the liver and accelerates oxidation of sugar in cells endocrine,hormone,internal secretion- the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a...
The present study has been performed to test for an effect of insulin and glucagon on liver cell volume. To this end, the effect of these hormones has been studied in isolated perfused rat livers and isolated rat hepatocytes. Insulin leads to rapid stimulation of cellular K+ uptake and ...
Effects on the Liver 68 6.8 Oedema 68 6.9 Interactions with Other Drugs 68 7 Clinical Studies of Insulin-replacement Therapy 69 7.1 Studies in Healthy Volunteers 69 7.2 Type-I Diabetes Mellitus 70 7.2.1 Complications 70 7.2.2 MDI in Children 72 7.2.3 MDI and Lipids 72 7.2.4 MDI and ...
a"In particular, fat in the liver interferes with its function and insulin sensitivity," Katz said. This starts a domino effect, he explained. “特别是,肥胖在肝脏干涉它的作用,并且胰岛素敏感性”, Katz认为。 这开始多米诺作用,他解释了。[translate]...
Zn acts with insulin-like function through a direct effect on insulin signaling regulation. Treatment of various cells with Zn significantly increased glucose transport and insulin signaling.15,40,78,103 The effect of Zn on insulin signaling was associated with stimulation of multiple components includi...
Paying more attention to diagnosis and treatment of insulin resistance will enhance the therapeutic effect and improve the prognosis of the patients. Traditional Chinese medicine has displayed its characteristics and advantage in treating insulin resistance. Investigation to chronic liver diseases based on ...