P1056 : Insulin resistance and liver damage are associated with early signs of left ventricular systolic dysfunction in patients with nonalcoholic fatty liver disease, independently of diabetes, hypertension and dyslipidemiadoi:10.1016/S0168-8278(15)31254-XVanni, E....
Context: Silymarin is the main flavonoid extracted from milk thistle, which has been used to treat liver diseases.Objective: The in vivo effect of silymarin on HFD-induced insulin resistance and fatty liver in mice was studied.Materials and methods: Male C57BL/6 mice were fed with high-fat ...
Hui et al. [8] reported that, in 260 patients with chronic hepatitis C, the HOMA- IR score, but not steatosis, was associated with the severity of fibrosis and accelerated the rate of progression. There- fore, regardless of the viral genotype and severity of liver damage, serum insulin ...
Insulin resistance is when cells in your muscles, fat, and liver don’t respond well to insulin, a hormone made by your pancreas that helps manage your blood glucose (blood sugar). Sometimes, insulin resistance is a short-term condition. But if left untreated for a long time, it could tu...
The mean value of IGF-1 was 65.9 ng/ml among virus-positive HCC patients, 79.5 ng/ml among virus-negative HCC patients, 110.8 ng/ml among patients with MLC, and 174.7 ng/ml among hospital controls. After controlling for the degree of liver damage, as assessed by prothrombin time and ...
Obesity and type 2 diabetes (T2D) are closely associated with hepatic steatosis (HS), which if untreated can advance to serious liver conditions. Since insulin promotes hepatic lipogenesis, reducing hyperinsulinemia may help in treating HS. E4orf1 is an adenovirus-derived protein that improves gluco...
Recent research has implicated the innate immune system in the pathophysiology of obesity-related liver disease. This review summarizes how innate immune processes, occurring both within and outside the liver, cause not only insulin resistance but also end-organ damage in the form of nonalcoholic ...
We found that both insulin receptor isoforms (IR-A and IR-B) are present in the fetal liver, and their expression is gestationally regulated. IR-B is highly expressed in the fetal liver; nonetheless, the percentage of hepatic IR-A isoform, which binds Igf2, was significantly higher in ...
1. hormone secreted by the isles of Langerhans in the pancreas; regulates storage of glycogen in the liver and accelerates oxidation of sugar in cells 词根词缀 词根:insul =island,表示"岛屿,sul有'单独'之意" adj. insular岛屿的,心胸狭窄的 ...
Cederna, JOncologyToledo-Pereyra, LH, Cederna, J Protection of liver allografts from ischemic damage prior to transplantation using insulin and catalase. In: Novelli, GP, Ursini, F eds. (1986) Oxygen free radicals in shock. S. Karger, Basel...