Insulin dependent diabetes (IDDM) was defined as diabetes diagnosed before age 30 years with insulin therapy begun within one year of diagnosis. All other types were considered non-insulin dependent diabetes (NIDDM). Analyses were performed for the whole sample and then for the NIDDM subgroup. ...
There is no single gene that “causes” type 1 diabetes. Instead, there are a large number of inherited factors that may increase an individual’s likelihood of developing diabetes. This is known as multifactorial inheritance. The genes implicated in the development of type 1 diabetes mellitus co...
et al. Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance. J. Clin. Invest. 84, 205–213 (1989). Article CAS PubMed PubMed Central Google Scholar Prager, R., Wallace, P. & Olefsky, J. M. In vivo kine...
RD SUMMARY I nsulin-dependentdiabetesmellitus(IDDM)is oneofthemostcommonchronicdiseasesin children;itsincidenceisincreasingintheAmeri- casandaroundtheworld.However,theetiology ofthisdisorderremainsunclear.Epidemiologicpat- terns,includingthehigherIDDMincidenceratesin CaucasianscomparedwithAfricanAmericansorHis- ...
Non-insulin-dependent diabetes mellitus (NIDDM), also known as type II diabetes, is characterized by abnormal glucosehomeostasis, resulting inhyperglycemia, and is associated with microvascular, macrovascular, and neuropathic complications. NIDDM is a complex disease with many causes. Both...
Insulin resistance causes type 2 diabetes; therefore, increasing insulin sensitivity is a therapeutic approach against type 2 diabetes. Activating AMP-activated protein kinase (AMPK) is an effective approach for treating diabetes, and reduced insulin receptor substrate-1 (IRS-1) protein levels have bee...
1231 IDIOPATHIC HYPERCALCIURIA (IH): A POTENTIAL CAUSE OF RENAL DISEASE IN CHILDREN WITH INSULIN DEPENDENT DIABETES MELLITUS (IDDM) 来自 Semantic Scholar 喜欢 0 阅读量: 24 作者:JI Malone,S Lowitt,JA Duncan,SC Shah,AW Root 摘要: Renal disease is a common complication of IDDM. The pathogenesis...
Perioperative neurocognitive disorder changes in elderly diabetes patients within 30 days after surgery: a retrospective cohort study Keke Song Rongrong Zhang Wei Gao Aging Clinical and Experimental Research (2023) Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, ne...
Koyama M, Wada R, Sakuraba H, Mizukami H and Yagihashi S (1998) Accelerated loss of islet beta cells in sucrose-fed Goto-Kakizaki rats, a genetic model of non-insulin-dependent diabetes mellitus. Am. J. Pathol. 153: 537–545 Article CAS PubMed PubMed Central Google Scholar Efanova IB...
Streptozotocin (STZ), a methylnitrosourea with a 2-substituted glucose, is widely used to induce experimental insulin-dependent diabetes mellitus (IDDM) in laboratory animals. A single injection of this selective pancreatic β cell toxin causes the induction of IDDM in murine and other rodent models...