Diabetes mellitus is a complex set of conditions that impacts 34 million Americans. While type 1 diabetes, type 2 diabetes, and gestational diabetes are most frequently encountered, there are many other types of diabetes with which healthcare providers a
(XVI); congenital malformations, deformations, and chromosomal abnormalities (XVII); symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified (XVIII); injury, poisoning, and certain other consequences of external causes (XIX); and factors influencing health status and ...
Future laboratory studies may determine exactly how 2-AAA regulates function of the pancreatic cells and how and when the body makes this molecule. On the clinical side, researchers might study whether the administration of these metabolites to humans causes similar effects to those observed in anima...
aType 2 diabetes mellitus 第二类型糖尿病mellitus[translate] a系统内部任何成员发生变化都会影响到其他成员,导致牵一发而动全身的系统重构 System interior any member changes to be able to affect other members, causes to pull one round to move the whole body system restructuring[translate] ...
Phenotypes of other systems produced by single gene knock-out could be accessed in Additional file 1: Table S9. Mediation analysis Alcohol consumption, body mass index (BMI), smoking, chronic pancreatitis, and type 2 diabetes mellitus were identified as risk factors for PC through previous ...
Immune system disorders lead to abnormally low immune activity (deficiency) or overactivity (autoimmunity). Immune deficiency diseases decrease the body's ability to fight infection, while autoimmunity prompts the body to attack its own tissues. Both are common causes of illness, and malfunctioning T...
et al. Large-scale association analysis of the Metabochip provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat. Genet. published online (12 August 2012); doi:10.1038/ng.2383. Speliotes, E.K. et al. Association analyses of 249,796 individuals reveal 18 ...
Crohn's disease (CD) is a complex autoimmune disorder presumed to be driven by complex interactions of genetic, immune, microbial and even environmental factors. Intrinsic molecular mechanisms in CD, however, remain poorly understood. The identification
The mutation is located in one of the alpha helices and would be expected to affect binding to the insulin receptor.: Next generation sequencing may prove to be an accurate and efficient method of genotyping for monogenic conditions with multiple potential causes. Analysis of further family members...
DiabetesRisk factorsDiabetes mellitus causes various problems in our life. With the big data boom in our society, some risk factors for Diabetes must still exist. To identify new risk factors for diabetes in the big data society and explore further efficient use of big data, the non-objective...