Genetic variants in the inositol phosphate metabolism pathway and risk of different types of cancer. Sci Rep. 2015;5:8473.Tan J, Yu CY, Wang ZH, Chen HY, Guan J, Chen YX, Fang JY: Genetic variants in the inositol phosphate metabolism pathway and risk of different types of cancer. ...
Myo-inositol Cancer 1. Background Inositol monophosphatase (IMPase) is an enzyme responsible for dephosphorylating myo-inositol monophosphate to generate phosphate-free myo-inositol [1]. Two IMPase isoforms have been identified in mammals, inositol monophosphatase 1 (IMPA1) and inositol monophosphatas...
aRemote bitmap cache is 遥远的数位映象的贮藏所是[translate] aadvanced bank 先进的银行[translate] aherbie herbie[translate] aMismatch repair 配错修理[translate] aInositol phosphate metabolism 肌醇磷酸盐新陈代谢[translate]
andinositolphosphate metabolism KarenAbel 1 ,RichardA. Anderson 1 andStephenB. Shears 2 * 1 DepartmentofPharmacology,Universityof WisconsinMedicalSchool,1300UniversityAvenue, Madison,WI53706,USA 2 InositideSignalingSection,NIEHS,111Alexander Drive,ResearchTrianglePark,NC27709,USA ...
Genetic variants in the inositol phosphate metabolism pathway and risk of different types of cancer Members of the inositol phosphate metabolism pathway regulate cell proliferation, migration and phosphatidylinositol-3-kinase (PI3K)/Akt signaling and are frequently dysregulated in cancer. Whether germline ge...
Formation and metabolism of inositol 1,3,4,5-tetrakisphosphate in liver. The inositol lipid pools of isolated rat hepatocytes were labeled with [3H]myo-inositol, stimulated maximally with vasopressin and the relative contents of... CA Hansen,S Mah,JR Williamson - 《Journal of Biological Chemistry...
Natural killer (NK) cells have important functions in cancer immunosurveillance, BM allograft rejection, fighting infections, tissue homeostasis, and reproduction. NK cell–based therapies are promising treatments for blood cancers. Overcoming their currently limited efficacy requires a better understanding of...
Energy metabolism is altered in cancer cells, which display enhanced glycolysis favouring production of lactate from glucose even in the presence of oxygen20 with other metabolic processes, including protein, nucleic acid and lipid biosynthesis, also being enhanced as part of the tumour metabolic ...
Biochemical and genetic data on the metabolism of inositol phosphates in the microorganism Dictyostelium are combined in a scheme composed of in five subroutes. The first subroute is the inositol cycle as found in other organisms: inositol is incorporated into phospholipids that are hydrolysed by PLC...
CANCER cell proliferationLOGISTIC regression analysisCANCER risk factorsCANCER genesMembers of the inositol phosphate metabolism pathway regulate cell proliferation, migration and phosphatidylinositol-3-kinase (PI3K)/Akt signaling and are frequently dysregulated in cancer. Whether germline genetic variants in ...