Cancer immunosurveillance by tissue-resident innate lymphoid cells and innate-like T cells. Cell 164, 365–377 (2016). Article CAS PubMed PubMed Central Google Scholar Dadi, S. & Li, M. O. Tissue-resident lymphocytes: sentinel of the transformed tissue. J. Immunother. Cancer 5, 41 (...
Innate lymphoid cells (ILCs) are positioned in tissues perinatally, constitutively express receptors responsive to their organ microenvironments, and perform an arsenal of effector functions that overlap those of adaptive CD4 + Tcells. Based on knowledge regarding subsets of invariant-like lymphocytes (...
Hematopoietic cells, including lymphoid and myeloid cells, can develop into phenotypically distinct 'subpopulations' with different functions. However, evidence indicates that some of these subpopulations can manifest substantial plasticity (that is, und
Innate lymphoid cells (ILCs) are a group of innate effectors with transcriptional, functional, and phenotypic similarities to various T helper (Th) subsets. Like Th subsets, ILCs are found atmucosal surfacesand play important roles in...
ID'ing innate and innate‐like lymphoid cells M Verykokakis,EC Zook,BL Kee - NIH Public Access 被引量: 0发表: 2014年 Cancer Immunosurveillance by Tissue-Resident Innate Lymphoid Cells and Innate-like T Cells Malignancy can be suppressed by the immune system in a process termed ...
(ILCs) are innateimmune cellsthat lack antigen specificity and are of lymphoid origin. They represent the innate immune counterparts of adaptive CD4 helper T cells. They are subdivided based on their cytokine profile into ILC1, ILC2, and ILC3 with Th1-, Th2-, and Th17-like profiles, ...
Innate lymphoid cells (ILCs) are a new and distinct family of innate immune cells that play an important role in immunity and inflammation. In this review,
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Intestinal intraepithelial T lymphocytes (IELs) are likely to play a key role in host mucosal immunity and, unlike other T cells, have been proposed to dif... G Eberl,RL Dan - 《Science》 被引量: 964发表: 2004年 Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues ...
cells can straddle innate and adaptive immunity, we found that signaling via antigen receptors, whose conventional role is to facilitate clonal T cell activation, was critical for the development of innate-like T cells but then was rapidly attenuated, which accommodated the cells' innate ...