Both naltrexone and the poly(d,L-lactide-co-glycolide) (PLG) polymer matrix in which it is encapsulated are well-tolerated. VIVITROL was approved by the Food and Drug Administration (FDA) in 2006 for once-monthly administration for the pharmacological treatment of alcohol dependence....
Naltrexone extended-release injectable (generic). (cover story)The article offers information on the generic drug naltrexone extended-release injectable with the brand name of Vivitrol which is classified as an opioid antagonist and used for treatment of alcohol dependence and as prevention for a ...
Both oral and injectable formulations are feasible to initiate prior to discharge for hospital inpatients identified as having an AUD. Copyright 2017 by the Research Society on Alcoholism. 展开 关键词: Alcohol Dependence Alcohol Use Disorder Naltrexone Hospital Treatment Engagement ...
Albayaty M, Linden M, Olsson H, et al. Pharmacokinetic evaluation of once-weekly and once-monthly buprenorphine subcutaneous injection depots (CAM2038) versus intravenous and sublingual buprenorphine in healthy volunteers under naltrexone blockade: An open-label phase 1 study. Adv Ther. 2017;34(2)...
Aripiprazole in the treatment of patients with alcohol dependence: a double-blind, com- parison trial vs. naltrexone. J Psychopharmacol. 2009;23:123–129. 58. Tiihonen J, Kuoppasalmi K, Föhr J, et al. A comparison of aripiprazole, methylphenidate, and placebo for amphetamine dependence. Am...
both the requirement for detoxification before naltrexone initiation and the treatment’s mechanism of action can increase the risk of fatal overdose [88]. Given the multiple inequities contributing to the overrepresentation of Black people in correctional facilities, the preference for naltrexone in this...
The use of naltrexone in the treatment of alcoholism is described in O'Malley et al.,Psychiatric Annals,November 1995, 11, p681-688, as well as numerous other publications. Patents of interest include U.S. Pat. Nos. 4,568,559; 4,623,588; 4,897,267; and 5,486,362. U.S. Pat....
Long-acting injectable naltrexone for the management of patients with opioid dependence. Subst Abuse 2011;5:1-9.Kiome, K. L., & Moeller, F. G. (2011). Long-Acting Injectable Naltrexone for the Management of Patients with Opioid Dependence. Substance Abuse, 5, 1-9....
METHODS: Fifty-four hospitalized veterans identified as having DSM-IV-TR alcohol dependence were randomized to receive (i) a 50mg oral naltrexone plus a 30-day prescription or (ii) a 380mg intramuscular naltrexone injection prior to discharge. Of 113 veteran inpatients deemed eligible based on ...
Reports on the research results which found that a new injectable form of naltrexone may offer a promising adjunct to the treatment of alcoholism in the U.S. Reduction in number of heavy drinking days by 25 percent by the injection given once a month; Use of the study results by Alkermes...