Rats were given daily naltrexone injections and then tested for taste reactivity to 10% alcohol 30 and 60 min after injection. Each reactivity trial (total of 4) was 60 sec during which 1 ml of fluid was infused. The rats' orofacial and body movements were videotaped and scored later. In...
Naltrexone, amu opioid receptorantagonist, was approved by the FDA for the treatment of alcoholism on the premise that it reduced the rewarding effects of alcohol. A new multicentre study, published in theNew England J. Medicine, revisited this hypothesis. The year-long trial compared the effect...
For opioid dependence, the treatment should be initiated with an initial dose of 25 mg. If no withdrawal signs occur, the sufferer may be started on 50 mg a day thereafter. For alcoholism, the usual recommended dose is 50 mg once per day for up to 12 weeks. Note – to reduce the ri...
Naltrexone(trade names includeReVia, Antaxone, Depade, Nalerona, Nalorex, Naltima, Naltrexon, Nemexin, Nodict, Trexan, Vivitrol) is an anti alcohol and opioid medication from drugs used in addictive disorders pharmacological group. This medicine is prescribed for the therapy of alcoholism, alc...
Efficacy of naltrexone and acamprosate for alcoholism treatment: a meta-analysis. Alcohol Clin Exp Res. 2001 Sep;25(9):1335-41. PMID: 11584154. View Summary + Center for Substance Abuse Treatment. Naltrexone and Alcoholism Treatment. Rockville (MD): Substance Abuse and Mental Health Services...
Introduction * Gene-Jack Wang gene-jack.wang@nih.gov 1 Laboratory of Neuroimaging, National Institute on Alcoholism and Alcohol Abuse, Bethesda, MD, USA 2 College of Mechanical and Electronic Engineering, Northwest Agriculture and Forestry University, Yangling, Shaanxi, China 3 Department of ...
We may speculate that those persons with FHϩ, at presumed greater risk for future alcoholism, have inherent lower opioid tone and therefore greater acute response to per- turbations in this stress-responsive modulation of the HPA axis. However, an alternative hypothesis, that these opioid-...
MH091537 (to YH), and the Yale Center for Translational Neuroscience of Alcoholism (to SK-S and SSO). This work would not have been possible without the work of the Yale PET center chemistry team, imaging technologists, and nurses. Special thanks go to Ralitza Gueorguieva, Ph.D., for ...
20030130322 Combination treatment for alcoholism and alcohol dependence July, 2003 Howard 6576256 Treatment of patients at elevated cardiovascular risk with a combination of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin 2003-06-10 Liang et al. 20030109546 Trea...
Naltrexone is a long-acting opioid antagonist used primarily in the management of alcohol and opioid dependence. The patient received intramuscular naltrexone for treatment of alcoholism. A week later, she presented with what appeared to be cellulitis at the site of injection. It progressed in ...