A corrosion inhibitor for a central heating system is provided in the form of a cream having low water content, which may be encapsulated within a water-soluble film, for example a poly (vinyl alcohol) film. The corrosion inhibitor product is more highly-concentrated than known liquid ...
The applicator may be fixed to any part of a heating system such as flow or return pipework. Two isolating valves 2 and 3 may be used for fixing, removal and functioning of the applicator. The applicator may be fitted with an air cock or plug for filling and venting and a drain cock ...
However, NMR spectroscopy can serve as a first-line method for the detection of counterfeit dietary supplements. This holds also true for other drugs that improve sexual performance, such as yohimbine, phentolamine, testosterone, and other androsterone derivatives. A similar example has recently been ...
Here we show that the aromatic character of the activation domain of the androgen receptor, a therapeutic target for castration-resistant prostate cancer, is key for its activity as transcription factor, allowing it to translocate to the nucleus and partition into transcriptional condensates upon ...
15., 16. The ability of mTOR inhibitors to induce autophagy and to reduce detrimental protein aggregates in neurons may be exploited for the treatment of other neurological disorders including Huntington’s,17., 18. Alzheimer’s,19 and Parkinson’s diseases.20 However, TORC1 inhibition by rapa...
The inhibition of protein tyrosine phosphatases 1B (PTP1B) and N2 (PTPN2) has emerged as an exciting approach for bolstering T cell anti-tumor immunity. ABBV-CLS-484 is a PTP1B/PTPN2 inhibitor in clinical trials for solid tumors. Here we have explored th
This optimized temperature range is highly beneficial for thermal energy storage applications. During heating, Fe2O3 decomposes, forming BaFe12O19, a stable iron source capable of promoting reversible CO2 chemical reactions. Consecutively, two reversible reaction steps were documented, the first being ...
Dipeptidyl peptidase-4 (DPP-4) inhibitors are glucose-lowering drugs for type 2 diabetes mellitus (T2DM). We investigated whether evogliptin® (EVO), a DPP-4 inhibitor, could protect against diabetic cardiomyopathy (DCM) and the underlying mechanisms. Eight-week-old diabetic and obese db/db...
We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with...
Immunocomplexes were washed three times with IP buffer and solved by heating for 5 min at 95 °C by western blotting analysis. To determine the relative levels of Hsp70-Bim PPI and Hsp70-Bag3 PPI, the Bim or Bag3 antibody (Ab) was added at a volume of 10 μl to the lysis buffer ...