The present invention provides a method for suppressing inflammation, which is in need of a cell by inhibiting NF-κB provide monoterpene composition. 这些组合物还可以含有载体分子,它使得单萜组合物能够透过膜. These compositions may also contain a carrier molecule, which composition is capable of ...
inhibition of nf-kb sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (vp16) or doxorubicin Inhibition of NF-kB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin. Oncogene - Arlt, Vorndamm, et al... A Arlt,J Vorndamm...
Inhibition of NF-kB renders cells more vulnerable to apoptosis induced by amyloid beta peptides. One of the mechanisms leading to neurodegeneration during Alzheimer''s disease (AD) is amyloid peptide neurotoxicity. In response to a variety of stress i... SM Cardoso,CR Oliveira - 《Free Radical...
INHIBITION OF NF-KB 专利名称:INHIBITION OF NF-KB 发明人:GUDKOV, ANDREI, V.,GUROVA, KATERINA, V.申请号:EP05791579 申请日:20050720 公开号:EP1771203A4 公开日:20100602 专利内容由知识产权出版社提供 摘要:Aminoacridines are inhibitors of NF-κB. Inhibiting NF-κB leads to reactivation of p53...
Thus, inhibition of NF-κB activity in cancer cells converts the LPS-induced proliferative response to an apoptotic response. Download: Download high-res image (303KB) Download: Download full-size image Figure 2. NF-κB inhibition blocks LPS-induced tumor proliferation, enhances LPS-induced tumor...
High glucose (22.2 mM) alone induced an increase in NF-κB activity. Treatment with inhibitors of NF-κB such as MG132, PDTC or expression of Ad-IκB-αM in VSMCs prevented VSMC proliferation and PAI-1 expression induced by high glucose. In conclusion, inhibition of NF-κB activity ...
The NF-KB transcription factor was affinity-purified from deoxycholate (DOC)-treated cytosol of HeLa cells and shown to contain both a 50-kD polypeptide (p50) with a DNA-binding specificity identical to that of nuclear NF-KB and a 65-kD protein (p65) lacking DNA binding activity, Electrophor...
The NF-kappaB transcription factor was affinity-purified from deoxycholate (DOC)-treated cytosol of HeLa cells and shown to contain both a 50-kappaD polypeptide (p50) with a DNA-binding specificity identical to that of nuclear NF-kappaB and a 65-kappaD protein (p65) lacking DNA binding activi...
we show that NF-κB is activated in murine dystrophic (mdx)hearts, and that cardiomyocyte ablation of NF-κB rescues cardiac function. This physiological improvement is associated with a signature of upregulated calcium genes, coinciding with global enrichment of permissive H3K27 acetylation chromatin...
Magnolol ameliorates lipopolysaccharide-induced acute lung injury in rats through PPAR-γ-dependent inhibition of NF-kB activation. Int Immunopharmacol. 2015;28(1):270–8. Article CAS PubMed Google Scholar Kutsenko N, Vesnina L, Kaĭdashev I. [Pioglitazone, an activator of PPAR-gamma, reduces...