PURPOSE:To form protoplasts even from bacteria having sparingly soluble cell walls effectively, by adding a cell wall synthesis inhibitory antibiotic to a culture of bacteria (B) during incubation as a pretreatment for dissolving B with an enzyme. CONSTITUTION:In dissolving coryneform bacteria, e.g....
Cell-wall-inhibiting antibiotic combinations with activity against multidrug-resistant Klebsiella pneumoniae and Escherichia coli. Clin Microbiol Infect 2014;20:O267-73.Hickman RA, Hughes D, Cars T, Malmberg C, Cars O (2013) Cell-wall-inhibiting antibiotic combinations with activity against multidrug-...
Nuclear export factor CRM1 be slowly reversible.161 Third, SINEs but not LMB treatment induces CRM1 degradation, followed by CRM1 re-synthesis after drug removal.59,165 Therefore, through bond reversibility and re-synthesis, nuclear export inhibition by SINE treatment is not permanent, but rather...
Integrins play a vital role in the interaction of extracellular matrix protein with the cell surface and in cell– cell adhesion in vertebrates. Misregulation of certain integrin receptors is linked to several diseases including cancer (Desgrosellier and Cheresh2010). Integrins are composed of an α...
it is also important to consider the conditions under which a resistant mutant cell might arise in a biofilm under treatment by a biofilm inhibitor. The focal cell, which would make EPS in spite of the inhibitor, is likely to be surrounded by the non-producer cells it derived from, and th...
Cell wall‐inhibitory antibiotics activate the alginate biosynthesis operon in Pseudomonas aeruginosa: roles of σ22 (AlgT) and the AlgW and Prc proteases A bioassay was developed to identify stimuli that promote the transcriptional induction of the algD operon for alginate biosynthesis in Pseudomonas...
Deoxynivalenol affects in vitro intestinal epithelial cell barrier integrity through inhibition of protein synthesis. Toxicol Appl Pharmacol. 2010;245(3):291–8. Article PubMed Google Scholar Ghareeb K, Awad WA, Bohm J, Zebeli Q. Impacts of the feed contaminant deoxynivalenol on the intestine ...
Observations support that endo- and exo-PG synthesis is governed by a sensitive regulatory network, which, in interaction with PGIP and cell wall degradation products, leads to generation or avoidance of elicitor-active oligomers, and, thus, may contribute to the development of the compatible or ...
Physiological functions facilitated by CYB561 encompass stress defense, cell wall modifications, iron metabolism, tumor suppression, and diverse neurological processes, such as memory retention [9, 10]. Studies reported that CYB561 is highly expressed in tissues of breast cancer patients and correlates ...
Inhibiting AIM2 may reverse this process. Overall, our study suggests that AIM2 is a reliable anti-inflammatory therapeutic target for AS. Inhibiting AIM2 expression may reduce foam cell formation and, consequently, inhibit the progression of AS plaques....