Two randomised trials and negative conclusion of the FDA about inhibitors of 5 alpha-reductase in prevention of prostate cancer need a revision of the indications of these drugs. After description of fundamentals data, review of the literature in PubMed library was performed to analyse the ...
(57)< Abstract > This invention 17 and 17 alkyl ketone 3 karubokishi of the steroid synthetic compound the turn group A ring analog, the medicine constituent which contains these chemical compounds, the steroid 5 redakutazeiso enzyme regards the manner which inhibits 1 which uses these chemical...
Black Tea Polyphenols Theaflavins Inhibit the Growth of LNCaP Prostate Cancer Cells through Suppressing Androgen Receptor and 5α-Reductase Activity... JK Lin,HH Lee,CT Ho - Dietary Supplements 被引量: 0发表: 0年 Tea polyphenols down-regulate the expression of the androgen receptor in LNCaP pros...
The invention relates generally to the use of anti-sense oligonucleotides, small interfering RNA, and ribozymes to modulate expression of the human steroid 5α-reductase gene and thereby modulate levels of dihydrotestosterone (DHT). Elevated levels of DH
PURPOSE:To obtain a testosterone-5alpha-reductase inhibitor having excellently preventing effects on removal of hair, hair growing and restoring effects as a hair tonic or skin external preparation, containing an extract of rosaceous plant. CONSTITUTION:Flower, pericarp, fruit, leaf, root, stem, etc...
The role or acting mechanism of testosterone 5alpha-reductase inhibitor in living body is the reduction of testosterone which is a major male hormone with testosterone 5alpha-reductase to keep excess state of dihydrotestosterone, which induces alopecia. Eugenol has testosterone 5alpha-reductase ...
After 24 h of treatment, the cells were incubated with 2 mg/mL 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) solution (MERCK, Germany) and incubated at 37 °C for 4 h. The mitochondrial reductase enzyme can change MTT (yellow color) into purple formazan ...
Lin, Theaflavin-3,3'-digallate and penta-O-galloyl-beta-D- glucose inhibit rat liver microsomal 5alpha-reductase activity and the expression of androgen receptor in LNCaP prostate cancer cells. Carcinogenesis, 2004. 25(7): p. 1109-18.
5α-reductase inhibiting agents, lysyl- and/or prolyl hydroxylase inhibiting agents, antioxidants, free radical scavengers and/or agents against atmospheric pollution, reactive carbonyl species scavengers, anti-glycation agents, antihistamine agents, antiviral agents, antiparasitic agents, emulsifiers, emollien...
5α-reductase inhibiting agents, lysyl- and/or prolyl hydroxylase inhibiting agents, antioxidants, free radical scavengers and/or agents against atmospheric pollution, reactive carbonyl species scavengers, anti-glycation agents, antihistamine agents, antiviral agents, antiparasitic agents, emulsifiers, emollien...