The latter includes the suppressive effects of the virus on the host immune system, stores ofvitamin Aand overall nutritional status. All of these may lead to an increased risk of super-infection with other (viral or bacterial) pathogens.Measlespneumonitis can be especially severe in...
In a recent Editorial [1], which commented on an article highlighting the predominant role of bacterial pneumonia as a cause of death in pandemic influenza, it was suggested to use C-reactive protein (CRP) to differentiate between viral and bacterial pneumonia. It was pointed out that the ...
a clear zonal distribution (eFig. 32-10C), and lobar consolidation (eFig. 32-10D), may be observed. Gram stain of the sputum fails to reveal significant bacteria, and bacterial culture yields sparse growth of normal flora, whereas viral cultures yield high titers ofinfluenza A virus. Such ...
Viral and bacterial clearance was delayed in 2-week-old offspring born to IAV-infected dams compared to offspring born to PBS-treated dams (Fig. 3k, l and Supplementary Fig. 6). These data show that offspring born to IAV-infected dams are more vulnerable towards secondary viral and bacterial...
Influenza is a highly contagious viral infection that typically occurs during the winter months. It is caused by influenza A, B, and C viruses. There are various subtypes of influenza A viruses, wh...
Complications include otitis media in chil- dren, sinusitis, viral pneumonia, secondary bacterial pneu- monia, exacerbation of underlying cardiac or pulmonary disease, myositis (including rhabdomyolysis), neurologic problems (seizures, acute encephalitis/encephalopathy, and postinfectious encephalopathy), Reye...
Infectious diseases caused by viral or bacterial pathogens are a major cause of death and morbidity worldwide, and constitute an ever-growing medical need. As such, they form a core area of research and development at Roche, with clinical development programmes focused on Hepatitis B...
and where they live. The most vulnerable population categories such as young children, the elderly and patients with comorbidities, are at greater risk of developing serious complications, including bacterial and viral pneumonia, and exacerbation of underlying medical conditions, which in some cases lead...
Clinical scales (i.e., the Centor scale) were used to evaluate the probability of bacterial infection. Laboratory tests were requested by a physician when clinically necessary to establish the final diagnosis or potential bacterial or viral aetiology. They included a complete blood count with ...
In both cases, the slow spread of the virus throughout the country possibly indicates that measures implemented to control the disease were effective, and consequently, no mass distribution or dissemination of the disease was recorded. The current study did not investigate other viral or bacterial ...