C-reactive protein (CRP), an acute-phase protein, is a predictor of cardiovascular mortality in nonrenal patient populations. In chronic renal failure (CRF), the prevalence of an acute-phase response has been associated with an increased mortality. Methods One hundred and nine predialysis ...
ofinducible nitric oxide synthase(iNOS) expression and activity in the lung and enhancement ofiNOSexpression and activity in the liver.182Pharmacologic application ofBV, an enzymatic by-product of HO activity, also decreased proinflammatorycytokine production, upregulated IL-10 levels, and reduced lung...
The inclusion criteria were as follows: patients had (1) aged >18 years; (2) an Eastern Cooperative Oncology Group performance status of 0; (3) a compensated liver function (Child-Pugh class A or B) and (4) complete baseline data. The exclusion criteria were as follows: patients had (...
An association between angiogenesis/inflammation status and tumor has been reported in various types of cancer. This study sought to assess the role of peripheral blood VEGF and some inflammation biomarkers in evaluating clinical response and prognosis i
The inflammatory response related to surgery (elective or anesthetized injury) and to trauma (accidental or unanesthetized injury) could be considered a surgical inflammation [1]. The surgical inflammation, as an inflammatory process, could be viewed as composed of a series of overlapping successive ...
Liver abnormalities in sepsis include cholestasis and hyperbilirubinemia. Gram-negative infections used to be the cause of cholestasis associated with sepsis [76]. Hyperbilirubinemia develops in sepsis particularly in the setting of bacteriemia. Hyperbilirubinemia precedes positive blood cultures in one ...
Relative expression of HMGB1 varies widely depending on tissue condition and type. Undifferentiated and inflamed tissues tend to have greater HMGB1 expression than their counterparts. Spleen, thymus and testes have relatively large amounts of HMGB1 when compared to the liver. Subcellular location varies...
The inclusion criteria were as follows: patients had (1) aged >18 years; (2) an Eastern Cooperative Oncology Group performance status of 0; (3) a compensated liver function (Child-Pugh class A or B) and (4) complete baseline data. The exclusion criteria were as follows: patients had (...
Inflammation, undernutrition-driven catabolism, and inadequate dietary intake are key drivers of DRM [1]. While medical inpatients with malnutrition have been shown to benefit from nutritional treatment, this may not be equally true for other patient populations, such as those in the ICU [1,5]....
Iron transport in the circulation occurs almost entirely bound to the beta globulin transferrin, which is synthesized in the liver [49]. Iron also binds to lactoferrin, which further regulates the proliferation and activation of monocytes/macrophages, lymphocytes and natural killer cells (NK-cells) ...