Fasting and overfeeding affect the expression of the immunity- or inflammation-related genes in the liver of poultry via endogenous retrovirus (ERV) It is known that nutrition and immunity are connected, but the mechanism is not very clear. Endogenous retroviruses (ERVs) account for 8-10% of...
TM6SF2 as new intestinal lipid player The gut–liver axis is of crucial importance in health and disease. TM6SF2 is a genetic risk factor for metabolic dysfunction-associated steatotic liver disease. Zhang, Yu et al. reveal that intestinal TM6SF2 critically affects the gut–liver axis. ...
摘要: Inflammation is the reaction of living tissues to various forms of injurious stimuli. It involves vascular, neurologic, humoral and cellular responses. The inflammatory process is designed to destroy, dilute or contain the injurious agent and pave the way for repair....
During inflammation, the liver is stimulated to release plasma proteins, collectively known as: acute phase reactants.The synthesis of many plasma proteins by the liver is increased during inflammation. These proteins, which can be either proinflammatory or anti-inflammatory in nature, are referred ...
Since the disruption in the oxidants and antioxidants balance as well as induction of inflammatory responses is a major mechanism involved in Cd-induced toxicity, the elimination of oxido-inflammation may be a viable therapeutic strategy to mitigate Cd toxicity. Asperuloside (ASP) is an iridoid glyco...
In this regard, chronic tissue inflammation has emerged as a key feature of obesity and T2D and is observed in insulin target tissues, such as adipose tissue, liver, muscle, and pancreatic islets. These observations have led to the term “immunometabolism,” which incorporates the underlying inter...
Inflammatory cells, such as neutrophils and macrophages, are the primary ROS/RNS releasing cells [2,18]. Originally, ROS were produced with the electron transport chain in mitochondria. The production process started with the one-electron reduction of O2 molecules for generating superoxide radical(O2...
Inflammation accompanies obesity and its comorbiditiestype 2 diabetes, non-alcoholic fatty liver disease and atherosclerosis, among othersand may contribut... ME Kotas,MC Gorecki,MP Gillum - 《Adipocyte》 被引量: 84发表: 2013年 Obesity and the development of type 2 diabetes: the effects of fatty...
the brain, bone, pleura, liver, or adrenal gland; by comparison, only 6 patients have been documented with progressed disease in the TCGA stage I cohort (Fig.1d). Distributions of age, smoking, sex, histologic and International Association for the Study of Lung Cancer (IASLC) grade in the...
Fructose consumption induces metabolic syndrome to increase cardiovascular disease risk. Cinnamaldehyde and allopurinol possess anti-oxidative and anti-inflammatory activity to relieve heart injury in metabolic syndrome. But the mechanisms of fructose-in