Tendon is a connective tissue that produces movement by transmitting the force produced by muscle contraction to the bones. Most tendinopathy is caused by prolonged overloading of the tendon, leading to degenerative disease of the tendon. When overloaded, the oxygen demand of tenocytes increases, an...
As you already know, a properly functioning gut is the foundation of vibrant health. Collagen is a main component of connective tissues, such as skin, joints and hair. The reason an 18 year old girl has beautiful skin compared to an 80 year old woman is because the 18 year old still ...
ADIPOSE tissuesCORONARY arteriesMYOCARDIAL infarctionADIPOSE tissue diseasesCARDIAC arrestCHEST painTERTIARY careBackground: The connective tissue around the blood vessels in the body (except cerebral vessels) is called perivascular adipose tissue (PVAT). Whenever there is a vascular pathology...
In this regard, chronic tissue inflammation has emerged as a key feature of obesity and T2D and is observed in insulin target tissues, such as adipose tissue, liver, muscle, and pancreatic islets. These observations have led to the term “immunometabolism,” which incorporates the underlying inter...
Through the repair process, endothelial cells give rise to new blood vessels, and cells called fibroblasts grow to form a loose framework of connective tissue. This delicate vascularized connective tissue is called granulation tissue. It derives its name from the small red granular areas that are ...
This review will focus on NLRP3, which is capable of assembling a large multi-protein platform, called the inflammasome, in order to mediate secretion of IL-1β and IL-18 to initiate the inflammatory process. We also present the role of NLRP1 and the corresponding inflammasome as a classical...
grade I indicating good healing (tissues slight redness and swelling about 25–50%); grade II indicating poor wound healing (tissues obvious redness, swelling with bleeding, more than 50% with connective tissue exposed); grade III indicating very poor wound healing (loss of epithelium beyond margi...
Endothelial barrier integrity plays a key role in maintaining a fluid balance between the circulation and tissues and vascular homeostasis. Studies indicate an association between endothelial dysfunction, subsequent elevation in the levels of endothelial factors, and development and intensification of coronary...
A class of new drugs, called "tumor necrosis factor (TNF) blockers", can block off the effect of a protein that mediates inflammation. hsbc.com.hk 一種全新的藥物種類稱為「腫瘤壞死因子抑制劑」(TNF blocker),可有效壓抑某種蛋白質所 產生 的 發 炎作 用。 hsbc.com.hk These cardiovascular di...
CD137 and ICOS. The presence of these molecules is the basis for the activation and function realization of Treg cells [2]. Treg cells were initially found in lymphoid tissues, with Treg cells in non-lymphoid tissues firstly proposed and studied in 2009. These tissues include skeletal muscle,...