either during intrauterine development or in postnatal life [1]. Although the CNS is normally protected by the meninges and blood-brain barrier (BBB), it is more vulnerable to infectious agents than any other tissue, due to the lack of a true lymphatic system, the...
Neuraminidase causes desialation of red blood cells, and possibly other blood cells and endothelium, by the removal of terminal neuraminic acid, which leads to unmasking of the Thomsen-Friedenreich antigen (T antigen) which is present on the surface of red blood cells, platelets, and glomerular ...
Paenibacillus Infection Causes Neonatal Sepsis and Subsequent Postinfectious Hydrocephalus in Ugandan Infantsdoi:10.2139/ssrn.4016548neonatal sepsispostinfectious hydrocephalusPaenibacillus16S sequencingmicrobiomeBackground: Paenibacillus thiaminolyticus was identified as an important contributor to postinfectious ...
Complications: hearing loss (33%), seizures, cognitive impairment, motor deficit, hydrocephalus, death (30-50% have sequelae). Prognosis: bacterial meningitis has higher mortality; viral usually self-limiting with good prognosis. Introduction
Disease in neonates may be severe, particularly if acquired early in pregnancy; symptoms include jaundice, rash, hepatosplenomegaly, and the characteristic tetrad of abnormalities: Bilateral retinochoroiditis Cerebral calcifications Hydrocephalus or microcephaly Psychomotor retardation Prognosis is poor. Many ...
During the occurrence and progression of cerebral malaria, the deposition of pRBCs in cerebral capillaries causes the adhesion of immune cells and platelets to vascular endothelial cells, thus resulting in encephalorrhagia, hydrocephalus and BBB permeability changes. Among them, the infiltration of T ...
50–80% of cases of neonatal HSV result from women who acquire genital HSV-1 or HSV-2 infection near term Congenital HSV (sepsis, microcephaly, hydrocephalus, chorioretinitis), vesicular lesions, central nervous system involvement (lethargy, poor feeding, seizures, developmental delay, epilepsy, bli...
The risk factors of intraspinal neuro TB mortality were diabetes mellitus, an age of more than 40 years, and diagnostic delays. The risk factors for intracranial neuro TB were HIV infection, stroke, hydrocephalus, lymphopenia, etc. (Contribution 6). Community-acquired pneumonia (CAP) is a ...
Of those who underwent neuroimaging, an associated hydrocephalus or ventriculitis was seen in 15.63% cases, and an associated abscess was seen in 6% of cases. In the following figures, brain MRI images are presented illustrating two cases: one of a patient diagnosed with meningitis (Figure 1) ...
In all patients, neurological impairments were identified, including microcephaly, a reduction in cerebral volume, ventriculomegaly, cerebellar hypoplasia, lissencephaly with hydrocephalus, and fetal akinesia deformation sequence (ie, arthrogryposis). Results of limited testing for other causes of microcephaly...