León-Rodríguez AD, Rivera-Pastrana D, Medina-Rivero E, Flores-Flores JL, Estrada-Baltazar A, Ordóñez-Acevedo LG, de la Rosa APB (2006) Production of penicillin acylase by a recombinant Escherichia coli using cheese whey as substrate and inducer. Biomol Eng 23:299–305 Article PubMed CAS...
chrysogenum was retained for a number of strains that are not used for the industrial production of penicillins and differ from P. rubens in some characteristics, such as their production of secondary metabolites [183]. However, in the vast majority of recent publications, it is still common ...
Versions Notes Abstract 8-Hydroxydaidzein (8-OHDe), anortho-hydroxylation derivative of soy isoflavone daidzein isolated from some fermented soybean foods, has been demonstrated to possess potent anti-inflammatory activity. However, the isoflavone aglycone is poorly soluble and unstable in alkaline soluti...
The HEK293 cells were grown in Dulbecco’s Modified Eagle’s Medium (DMEM) supplemented with 10% fetal bovine serum, 50 UI/mL penicillin and 50 mg/mL streptomycin at 37 °C in a humidified 5% CO2 atmosphere. The cells used in this work (HEK293) were kindly provided by “Pasteur ...
coupled a CFD model with a 9-pool metabolic model to assess the effect of substrate heterogeneity on industrial-scale production of penicillin, providing guidance for rationally designing scale-down models [69]. Mechanistic and data-driven modeling are the main two crucial techniques for bioprocess ...
Versions Notes Abstract Dry eye (DED) is a prevalent disease with immune-mediated inflammation as the principal pathophysiological etiology. Olive pomace, the major by-product of the olive oil industry, is rich in high-value polyphenols. Their anti-inflammatory and immunomodulatory activities were dete...
Versions Notes Abstract Continuous bioprocessing using cell retention allows the achievement of high space-time yields for slow-growing organisms such as halophiles. However, the lack of efficient methods for monitoring and control limits the application of biotechnological processes in the industry. The...
Versions Notes Abstract Cryopreservation and lyophilization processes are widely used for conservation purposes in the pharmaceutical, biotechnological, and food industries or in medical transplantation. Such processes deal with extremely low temperatures (e.g., −196 °C) and multiple physical states of...
In references [20,21], the authors developed mathematical models (soft sensors) to predict the concentrations of sulfur dioxide and hydrogen sulfide at a sulfur production plant. Furthermore, such models are presented for the penicillin fermentation process [22], the industrial polyethylene process [...
Production environments affect the specificity and the density of mycobiota that overgrow the surface of dry-fermented meat products during ripening, and consequently also the quality and safety of these products [2,3]. Although the presence of surface moulds is generally appreciated because of ...