The objective of this study was to study the composition and characteristics of the soil microbial communities that had been exposed to long-term selection pressure caused by the industrial production of penicillin G. Soil samples from four sites among the penicillin G production plant were analysed...
aOthers point out that industrial strains of penicillin production are tolerant to high levels of glucose and question the use of substrate inhibition terms in Eq. (10). 其他在Eq指出青霉素生产工业张力对高水平是宽容葡萄糖并且对对基体禁止期限的用途表示怀疑。 (10). [translate] ...
a全世界75%的青霉素工业盐,80%的头孢菌素类抗生素,90%的链霉素类抗生素产于中国。 The world 75% penicillin industry salt, 80% cephalosporin class antibiotic, 90% chain mildew element class antibiotic produces in China.[translate]
Even after many years of research and industrial practice, the production of penicillin G in fed-batch fermentation by Penicillium crysogenum continues to attract research interest. There are many reasons: the commercial and therapeutic importance of penicillin and its derivatives, the complexity of ...
Application of yeasts in traditional biotechnologies such as baking, brewing, distiller's fermentations, and wine making, involves them in exposure to nume... Attfield,V Paul - 《Nature Biotechnology》 被引量: 903发表: 1997年 Industrial production of β-lactam antibiotics The industrial production...
Fungi have been used in penicillin, lovastatin, and other significant medicines. Consumers increasingly prefer natural compounds over synthetic chemicals, even in industrial sectors that produce commodity chemicals. The study stated that the application of fungi needs to be explored since it is a highly...
1940sProduction of penicillin by fermentation (USA) 1950sDesign and scale-up of large aerated fermentors 1970sMore than 100 new drugs and vaccines produced by bioprocesses 1980sControl of fed-batch bioreactors Nowadays, the development of industrial technologies is mainly focused on moving toward the...
(1984). Enzymatic conversion used in the production of penicillins and cephalosporins. InBiotechnology of Industrial Antibiotics. Vandamme, E.J. ed. Vol22, pp 171–224, New York: Marcell Dekker. Google Scholar Shimizu, M., Okachi, R., Kimura, K. & Nara, T. (1975).Agr. Biol. Chem...
Enhanced penicillin production by oligosaccharides from batch cultures of Penicillium chrysogenum in stirred‐tank reactors Alginate and galactomannan-derived oligosaccharides enhanced the production of penicillin G when added to stirred tank reactor cultures of Penicillium chry... B Ariyo,C Tamerler,C Bucke...
A structured kinetic model previously developed to describe the growth, differentiation, and penicillin production of Penicillium chrysogenum has been enha... C G.,Paul,and,... - 《Biochemical Engineering Journal》 被引量: 35发表: 1998年 A Study on the Interpolation Algorithm to Improve the Blur...