Indolinones substituted in six locations, their manufacture and their application as medicine6-Carboxy-3-(anilino- or cycloalkylamino-methylene)-indolin-2-one or -thione derivatives (I) are new. 6-Carboxy-3-(anilino- or cycloalkylamino-methylene)-indolin-2-one or -thione derivatives of ...
Roth, Gerald JuergenHeckel, ArminLehmann-lintz, ThorstenKley, JoergHilberg, FrankVan Meel, JacobusUS20030092756 * Apr 4, 2002 May 15, 2003 Roth Gerald Juergen Substituted indolinonesUS20030092756 Apr 4, 2002 May 15, 2003 Roth Gerald Juergen Substituted indolinones...
These responses were either comparable or superior to sunitinib, which had IC50 values of 4.7 μM and 4.5 μM in HuH7 and HepG2, respectively. Table 1. Indolinones synthesized. Compounds 39–48 were synthesized with substituents R′ and R″ on benzylidene-indolinone as shown below. Number...
Shetgiri NP, Nayak BK (2005) Synthesis and antimicrobial activities of oxadiazoles, phthalazines and indolinones. Ind JChem 44B: 1267-1272.Shetgiri NP, Nayak BK. Synthesis and antimicrobial activities of oxadiazoles, phthalazines and indolinones. Indian J. Chem., 44B, 1267-1272 (2005)....
Indolinones of Formula II above may be prepared by cyclization of the corresponding alpha-chloro diphenyl amide. Nitriles of Formula IV above are prepared by reaction of a compound of Formula II above with a halide of Formula Hal-(C n-1 H 2n-2 )CN. Halides of Formula VI above are ...
ChemInform Abstract: Synthesis of Some New 1-Substituted 5-Bromo-3-aryloxy Acetyl Hydrazono-2-indolinones as Potential Antibacterial Agentsindole derivatives, isoindole derivativesA series of [4-(6H/bromo-4-oxo-2-phenyl-3(4H)-quinazolinyl)phenoxy]acetic acid (1,2-dihydro-1-H/methyl-2-oxo-...
SUBSTITUTED INDOLINONES USEFULAS HERBICIDE 来自 百度文库 喜欢 0 阅读量: 7 申请(专利)号: JP特願平4-358800 申请日期: 19921228 公开/公告号: JP特開平5-255246A 公开/公告日期: 19931005 申请(专利权)人: AMERICAN CYANAMID CO アメリカン・サイアナミド・カンパニー 发明人: ME Condon...
3-hydroxy welwitindolinones and pyrrolidinoindoline-type alkaloid, CPC-1 are some examples of a growing list of bioactive 3-substituted-3-hydroxy-2-oxin... Peddibhotla,Satyamaheshwar - 《Current Bioactive Compounds》 被引量: 54发表: 2009年 Synthesis of Substituted 1,2,3,4-Tetrahydro-1-thi...
Oxidized welwitindolinones from terrestrial Fischerella spp. [Erratum: June 1999, v. 62 (6), p. 940.] JI Jimenez,U Huber,RE Moore,... 被引量: 176发表: 1999年 Oxidized Welwitindolinones from Terrestrial Fischerella spp. Jimenez,J.I.,Huber,U.,Moore,R.E.,Patterson,G M.L.Oxidized...
Novel substituted indole inone, their preparation and their use as medicamentsThe invention relates to indolinones of general formula (I), wherein R1 to R3 have the meanings given in claim 1, to their isomers and to their salts, ... 被引量: 0发表: 0年 ...