VIP 药材来源(中文)白花丹 药材来源(英文)Plumbago zeylanica 药材来源Whiteflower Leadword 化学成分名称(英文)Indole-3-Carboxaldehyde 化学成分名称(中文)吲哚-3-甲醛 CAS号487-89-8;1093452-52-8;4877-89-8 分子式C9H7NO 分子量145.15798 靶点Xanthine dehydrogenase/oxidase;Xanthine dehydrogenase;Xanthine ...
DearEditor,Indole-3-carboxaldehyde(ICA)is a gut microbe-derived tryptophan metabolite.Here,we explored the role of ICA in atherosclerosis.Plasma tryptophan metabolites were measured in healthy individuals and patients with atherosclerosis(Supplementary Table S1).The latter group showed disturbed tryptophan ...
Furthermore, the control of biofilms and swarming efficiency by quorum sensing pathway of the pathogen was modulated by ICA, which was substantiated using real-time analysis for opaR, cpsA, and lafA genes. This study divulged the efficacy of ICA as an antibiofilm agent against V. parahaemolyticus...
The molecular interaction, stability and intramolecular charge transfer of ICA were studied using frontier molecular orbitals (FMOs) analysis and Mulliken atomic charge distribution shows the distribution of the atomic charges. The presence of intramolecular charge transfer was studied using natural bond ...
doi:10.1016/j.ica.2019.03.001Morzyk-Ociepa, BarbaraSzmigiel-Bakalarz, KseniaNentwig, MarkusOeckler, OliverMalik-Gajewska, MagdalenaTurlej, ElizaWietrzyk, JoannaMichalska, DanutaElsevier ScienceINORGANICA CHIMICA ACTA
doi:10.1016/j.ica.2019.03.001Barbara Morzyk-Ociepa aKsenia Szmigiel-Bakalarz aMarkus Nentwig bOliver Oeckler bMagdalena Malik-Gajewska cEliza Turlej dJoanna Wietrzyk dDanuta Michalska cElsevier BVInorganica Chimica Acta