Interleukin-1β increases the risk of gastric cancer through induction of aberrant DNA methylation in a mouse model.Interleukin-1β increases the risk of gastric cancer through induction of aberrant DNA methylation in a mouse model.doi:10.3892/ol.2016.4296gastric...
il-8 polymorphism increases the risk of gastric cancer, gastric ulcer, and atrophic gastritis in japanese populationdoi:10.1016/S0016-5085(03)82035-8Ohyauchi, MotokiImatani, AkiraOhara, SyuichiSekine, HitoshiKoike, TomoyukiIijima, Katsunori
for well-known gastric cancer risk factors such as smoking (RR=1.17;95%CI:1.01-1.34) and H.pylori infection (RR=2.35;95%CI:1.24-4.46).CONCLUSION:Pre-existing diabetes mellitus may increase the risk of gastric cancer by approximately 19%.This effect seems to be unrelated to geographical ...
Key Words: Disease association; Diabetes mellitus; Gastric cancer; Incidence; Risk; Meta-analysis Citation: Yoon JM, Son KY, Eom CS, Durrance D, Park SM. Pre-existing diabetes mellitus increases the risk of gastric cancer: A meta-analysis. World J Gastroenterol 2013; 19(6): 936-945 URL...
2. Colorectal cancer Colorectal cancer is the first cause of cancer death among non-smokers in affluent countries, and the five-year survival (approx. 60%) improves too slowly with the advances in the treatment of the disease. Eating processed meat increases the risk of developingcolorectal cance...
The results of a systematic review and meta-analysis suggest that the mortality risk for colon cancer patients begins to increase with any avoidable delay in adjuvant chemotherapy beyond 4 weeks. The results of a systematic review and meta-analysis suggest that the mortality risk for colon c...
The factors that determine the link between infection and risk of gastric cancer are complex and not well understood, possibly relating to both the genetic back- ground of the individual, and to the genetic variation of H. pylori. Strains of H. pylori that carry the cytotoxin- associated (...
Caudal-related homeobox 1 (CDX1), an intestinal-specific transcription factor, has been reported to have vital roles in gastric intestinal metaplasia (IM). Although IM is a high-risk factor for gastric cancer (GC), the specific role of CDX1 in GC is larg
Similarly, oncogenic lnRNAs namely HULC, UCA1 and PVT1 epigenetically silence the expression of certain genes such as NKD2, p21, E-cadherin, p15, p16 via H3K27 trimethylation by directly binding to EZH2 of the PRC2 complex in colorectal carcinoma, gallbladder and gastric cancer (Cai et al...
(AIM2) were also involved in carcinogenesis8,9,10. Dysregulation of NOD2 was reported to be involved in the pathogenesis of Crohn’s disease (CD) and colitis related colon cancer7; and NOD2 gene polymorphisms have been associated with increased risk of lymphoma, colorectal, gastric, breast, ...