Pancytopenia with marrow hypocellularity and increased marrow blast cells were characteristic hematopathologic features. Marrow hypocellularity was moderate to severe (>25%) in over half of the cases and mild to moderate (>25, >35%) in the remainder. Blast cells were the predominant cellular ...
Each data point represents a different donor (fetal liver n = 4, cord blood n = 4 with Figure S4F, adult bone marrow n = 5). (B) Human CD34+ cells from fetal liver were cultured for 7 days in vitro in the presence or absence of 1 mM NR and were transplanted in primary (n =...
3c,d) confirmed that Serpinb1a is increased in dystrophic muscle compared to wild type muscle at both ages examined and that it tends to concentrate at sites of increased cellularity, which are the sites of focal muscle damage and inflammation (Fig. 3c,d). Serpinb1a is an endogenous ...
bone marrow (Fig.2e) but with an apparent decrease in the immune cellularity (Fig.2b, right). Furthermore, in those mice, there appeared to be a reduction in the donor-derived component (i.e. Atg5i bone marrow-derived) of the peripheral blood (Supplementary Fig.5g). Largely consistent ...
Cellularity and cartilage matrix increased in hypertrophied ligamentum flavum: histopathological analysis focusing on the mechanical stress and bone morpho... Wakitani, and H. Nakamura, "Cellularity and cartilage matrix increased in hypertrophied ligamentum flavum: histopathological analysis focusing on the ...
hours after the injection of DS the number of endogenous spleen colonies increased following the administration of mexamine and cystamine, the number of haemopoietic stem cells surviving in the femur after irradiation increased, and recovery of the cellularity of irradiated bone marrow was accelerated....
Pathological examination of BM from anemic mice revealed normal cellularity but reduced erythropoiesis with expansion of myeloid cells. FACS analyses revealed expansion of myeloid (CD11b+, Gr-1+) and immature erythroid population (CD71+Ter119+/dim) in the spleen and BM, and increased CD11b+, Gr...
Table 2.Patient characteristics for Treg-cell assessment in lymph node biopsies. Patient characteristics including gender, age at analysis, first diagnosis, therapy, and frequency of Tregcells. (f: female, m: male; no tx: no therapy; mc: mixed cellularity; ns: nodular sclerosing). ...
Bone marrow exhibits decreased cellularity and increased apoptosis, but no change in global cytosine methylation, following ablation of the Cxxc1 gene.Kristin T. ChunBinghui LiErika DobrotaCourtney TateJeongHeon LeeShehnaz KhanLaura HanelineHarm ...
Bone marrow cellularity of C/EBPepsilon -/- and wild-type mice was 95% and 65%, respectively. The C/EBPepsilon -/- mice had an expansion in the number of their CFU-GM/femur. The number of myeloid committed progenitor cells in the peripheral blood and the spleen of these mice was ...