制剂临床配伍相容性研究(Clinical in use stability study,CIU) 目的就是在实验室评估临床配伍过程对药物物理化学或微生物属性的影响,通常包括与稀释剂的相容性、剂量准确性、与给药装置的相容性、模拟输液及配伍后溶液储存条件和有效期等。 一、稀释剂相容性 临床上最常用的等渗静脉稀释液为①0.9%氯化钠注射液(生...
Use of MALDI-MS with solid-state hydrogen deuterium exchange for semi-automated assessment of peptide and protein physical stability in lyophilized solids 热度: EP25-A Evaluation of Stability of in Vitro Diagnostic Reagents 热度: 英文科学报告被动语态的使用及翻译对比研究A Comparative Study on the Use...
in use stability专题研究 In use stability专题研究 Zhulikou431 内部培训 2012 中国
In the case of active substances, articles involving 21 active substances were identified.Expert opinion As a result of the study, we summarized in-use stability study designs and in-use shelf life settings for nonsterile formulations such as formulation (strength), container closure system, ...
This study aimed to evaluate in-use stability data of MabThera subcutaneous drug-product solution in single-use syringes for subcutaneous administration according to the European Medicines Agency guideline. The drug-product solution was exposed to material contact surfaces of five different administration...
Participants’ heads were secured in position using a custom-built head holder during the scanning process to ensure stability and accuracy. High-resolution structural images were acquired with the following parameters: echo time = 4.16 s, repetition time = 9.6 s, flip angle =...
We examined the relationship between venue stability and consistent condom use (CCU) among female sex workers who inject drugs (FSW-IDUs; n = 584) and were enrolled in a behavioural intervention in two Mexico-USA border cities. Using a generalized estimating equation approach stratified by client...
All scores had good internal consistency (alpha >.75), presented high temporal stability (>.76), discriminated between patients and controls, and presented strong ( ρ >.81) correlations with the Sexual Addiction Screening Test (except for the violence domain=.40) and moderate correlations with...
et al. Detection of recombinant bovine somatotropin in milk and effect of industrial processes on its stability. Anal. Chim. Acta 672, 45–49 (2010). Article Google Scholar Regal, P., Lamas, A., Fente, C. A., Franco, C. M. & Cepeda, A. Tracing (r)bST in cattle: Liquid-based...
In this study, we investigated the PNUE, photosynthesis, leaf N allocation and mesophyll conductance to CO2inD. odorifera,E. fordii,B. alnoidesandC. hystrixseedling leaves that were exposed to different soil N treatments. The objectives of our study were to 1. understand the effects of soil ...