(1984). An improved colorimetric assay for T cell cytotoxicity in vitro. Journalof Immunological Methods, 68: 205-215.Müllbacher A, Parish CR, Mundy JP (1984a). An improved colorimetric assay for T cell cytotoxicity in vitro. J Immunol Methods 68: 205–215...
The low cytotoxicity level with HER2-XPAT protein in HER2-expressing tumor cell lines was partly due to a low degree of proteolytic cleavage during the in vitro assay. This is supported by further reduction in cytotoxicity seen with HER2-XPAT protein lacking one or both of its protease cleavag...
Chitinase-3-like-1 (Chi3l1) is known to play a significant role in the pathogenesis of Type 2 inflammation and cancer. However, the function of Chi3l1 in T cell and its clinical implications are largely unknown. Here we show that Chi3l1 expression was increased in activated T cells, especiall...
Platinum-based chemotherapy is the main treatment element to achieve cure for patients with metastatic germ cell tumours. Drug resistance in testicular ger... S,Koch,F,... - 《British Journal of Cancer》 被引量: 168发表: 2003年 Cytotoxicity of fluoride on human pulp cell cultures in vitro ...
Determination of cell viability is an established measurement endpoint recommended by the ISO standard for in vitro basal cytotoxicity assessment [30], which is very important in determining the cytocompatibility of the two monomers. Based on cytotoxicity assay, the critical tolerant concentration represent...
Cytotoxicity of Echinococcus granulosus cyst fluid in vitro In a cytotoxicity assay, using rat spleen cells as target cells, Echinococcus granulosus cyst fluid from cattle exerted a marked degree of cytotoxicity in ... JM Annen,P Khler,J Eckert - 《Zeitschrift Für Parasitenkunde》 被引量: 58发...
microscopy (SEM), transmission electron microscopy (TEM), X-Ray diffraction (XRD), atomic force microscopy (AFM), and dynamic light scattering (DLS) methods. Cell internalization, cytotoxicity assay (MTT), apoptosis induction, and gene expression of SPION@Cs-PTX-PEG-FA were estimated in ...
Moreover, many cell types within the native TME have specific functional phenotypes that are a challenge to replicate within in vitro systems. For example, TME-based CD8 T cells exhibit naïve, cytotoxic, or exhausted functional phenotypes [2]. These cellular functional “states” have a ...
Objective: To evaluation the cytotoxicity of three kinds of perforation repair materials on human periodontal ligament fibroblasts( HPDLF)in vitro. Methods: The proliferation of HPDLFs to three perforation repair materials were examined by MTT-assay at days 1, 3 and 5 days,The mRNA expression lev...
Importantly, we could show that the AdCAR T-cell platform allows the use of TFIs that abrogate target-induced T-cell dysfunction. Methods In vitro cytotoxicity assays and pAML culture AdCAR T cells or untransduced (mock) T cells were co-cultured with MV4-11, HL-60, or OCI-AML-3 cells...