The use of in vitro culture as a monitoring system is discussed.doi:10.1016/S0045-6535(97)10113-8Bruschi, PSchiff, SBennici, AMori, BChemosphereBruschi, S.P., Bennici, A. & Mori B. (1998). An example of in vitro test to study the effects of surfactants in plant material. ...
For example, the osteogenic activity of bone integration and efficiency in bone repair implants are now subject to higher standards. Ti alloys, being inert metals, do not inherently possess bioactivity. However, researchers have discovered that by modifying the surface of an alloy, the desired ...
40,47. Sequences of mitochondrial DNA (mtDNA) may or may not be present depending on the context and/or cell line39. Other studies have shown that selective sorting of specific DNA sequences may occur. For example, a study investigating different prostate cancer cell-derived...
For example, PTGS1 plays an important role in cell protection [62, 63] while AHR participate in the regulation of cell cycle [64]. PRKCA is involved in cell proliferation, apoptosis, differentiation, migration and adhesion [65] while VEGFA can induce endothelial cell proliferation, promote cell...
One important contributor is the lack of cellular heterogeneity that is a hallmark of tumors in vivo, in typical in vitro models [121,122]. For example, cell lines grown in conventional 2D culture are intrinsically homogenous, which is further reinforced by the lack of cellular and acellular...
[Methods in Molecular Biology] T-Cell Trafficking Volume 1591 || In Vitro and Ex Vivo Models to Study T Cell Migration Through the Human Liver Parenchyma Cell-based therapy has been proposed as an alternative to orthotopic liver transplantation. The novel transplantation of anin vitro-generated li...
(S,R,S)-AHPC, VHL knockout or the use of a control AZ’6421 epimer with reduced binding to VHL all gave a reduction in Dmaxcompared to AZ’6421 alone. This is in contrast to other reported PROTACs where, for example, loss of VHL recruitment led to complete rescue of AR or Brd4 ...
A few strains are derived from spontaneous formation, for example, pigs with hypercholesterolemia and aortic stenosis share several traits with human CAVD (Sider et al. 2014; Skold et al. 1966). The natural Nox2 inhibitor, celastrol, was found to effectively alleviate CAVD by inhibiting Nox2-...
Another example of sperm cooperative behavior is discovered in deer mice, where sperm are able to recognize and aggregate with the most genetically related sperm and form cooperative groups to increase their velocity against unrelated sperm35. The results obtained in this study do not contradict Fo...
The phytochemical curcumin was shown to have the power to decrease Aβ oligomerization and cell proliferation in the in vitro study; however, when it was injected into mice, it showed poor bioavailability [231]. Curcumin was formulated by using nanoliposomes, which improved the bioavailability ...