The present disclosure provides an in vitro cell based potency assay to determine the relative potency of a composition, including a pharmaceutical composition, comprising an mRNA encapsulated in a lipid nanoparticle (LNP) as compared to a reference sample. Also provided is a process for releasing ...
Recruiting Talents 爱思益普寻求有志于人类健康事业的有识之士加入,与爱思益普一起成长,以我们的产品造福于人类。 Efflux transporters facilitate the export of compounds from the cell, both in some cellular assays, also in ADME studies. These transporters belong to the ATP-binding cassette (ABC) family....
ReadyCell provides you with everyday solutions for yourin vitroADME-Tox needs Permeability Tools Drug-Transporter Interactions Blood Brain Barrier Cytotoxicity We facilitate and streamline drug discovery and development study assays withavailablecell-based plates that arestored and transported atroom temperatu...
–Advanced in vitro exposure systems Inhalation Toxicology We have over two decades of experience in designing, producing and installing cell culture exposure systems specifically for your research needs. Discover our cell culture exposure equipment Skin Exposure VITROCELL Skin modules are a powerful alter...
A biology-based dynamic approach for the modelling of toxicity in cell-based assays. Part I: Fate modelling There is a need to integrate existing in vitro dose-response data in a coherent framework for extending their domain of applicability as well as their extrapolation potential. This ...
cell biology and developmental biology. Here we use tumor cell migration and invasion as an example and describe two related assays to illustrate the commonly used, easily accessible methods to measure these processes. The first method is the cell culture wound closure assay in which a scratch is...
The red box highlights the three biological replicates from the in vitro cell representation samples, showing high correlation. The black lines on the right side of the graph represent dendrograms of sample hierarchical clustering based on the distance between samples (calculated on the Pearson ...
One of the main challenges in cell therapy for muscle diseases is to efficiently target the muscle. To address this issue and achieve better understanding of in vivo cell fate, we evaluated the relevance of a non-invasive cell tracking method in the Gold
for PCR based cell-free protein synthesis LEXSY in vitro Translation Cell ExtractEGE-260 for cell-free protein synthesis Reference publication 1 Reference publication 2 Reference publication 3 BIOZ Product Citations Please click the arrow on the right to expand the citation list. Click publication ti...
Clonogenic assay or colony formation assay is an in vitro cell survival assay based on the ability of a single cell to grow into a colony. The colony is defined to consist of at least 50 cells. The assay essentially tests every cell in the population for