In situ, literally stands for “in place of”, “at the original site of”, “in the natural position of” or “in the undisturbed shape or orientation of”.
Long-term lineage commitment in haematopoietic stem cell gene therapy 造血干细胞基因治疗中的长期血统承诺 Adult skull bone marrow is an expanding and resilient haematopoietic reservoir 成年颅骨骨髓是一种持续扩张且有弹性的造血库 Broadly inhibitory antibodies to severe malaria virulence proteins 对严重疟疾毒性...
Andy Balmer: You say you're working on a synthetic biology project. Why do you call it that? Academic Molecular Biologist 1: Why do I call it that? Partly because that is where the idea [for my work] came from. The network I got involved with was badged as a synthetic biology ...
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In the unprecedented single-cell sequencing and spatial multiomics era of biology, fluorescence in situ hybridization (FISH) technologies with higher sensitivity and robustness, especially for detecting short RNAs and other biomolecules, are greatly desired. Here, we develop the robust multiplex π-FISH...
G protein-coupled receptors (GPCRs) are important signal transducers that are phosphorylated upon activation at intracellular serine and threonine residues. Although antibodies that specifically recognize the phosphorylation state of GPCRs have been avai
Biology of Stem Cells in Human Umbilical Cord Stroma: In Situ and In Vitro SurveysHumanUmbilical cordMesenchymal stem cellsDifferentiationCytoskeletonCells in the umbilical cord stroma have gained attention in recent years; however, differentiation to certain lineages in humans has been demonstrated in ...
(6.8 Gb/1 C) together with methylome and transcriptome data to explore its astonishing biology. We also present a refined, high-quality assembly ofGnetum montanumto enhance our understanding of gnetophyte genome evolution. TheWelwitschiagenome has been shaped by a lineage-specific ancient, ...
The body of knowledge regarding the classification and evolution of freshwater mussels in the family Unionidae (Bivalvia) in Indochina has recently increased. However, the taxonomic revision of all extant taxa in the region is still ongoing. In this stud
The freshwater planarian Schmidtea mediterranea has emerged as a powerful model for studies of regenerative, stem cell, and germ cell biology. Whole-mount in situ hybridization (WISH) and whole-mount fluorescent in situ hybridization (FISH) are critical methods for determining gene expression patterns...