In situ, literally stands for “in place of”, “at the original site of”, “in the natural position of” or “in the undisturbed shape or orientation of”.
In this issue of Cell, Hu et al. use cryo-electron tomography to reveal an unprecedented level of details regarding the architecture of this machine and the conformational changes that occur during its assembly.doi:10.1038/nrmicro.2017.36StarlingShimonaNat Rev MicrobiolNature Reviews Microbiology...
In subject area: Biochemistry, Genetics and Molecular Biology In situ hybridization is the process of establishing a noncovalent sequence-specific interaction between a labeled complementary DNA or RNA strand (ie, probe) and a specific DNA or RNA sequence of interest in a section of tissue [3]....
View Book Chapters Publish with IntechOpen Next chapter Genomic in situ Hybridization in Triticeae: A Methodological Approach By Sandra Patussi Brammer, Santelmo Vasconcelos, Liane Balvedi Poersch, Ana Rafaela Oliveira and Ana Christina Brasileiro-Vidal 5,766 downloads Written...
Molecular Biology SHARON P.WILCZYNSKI, inModern Surgical Pathology (Second Edition), 2009 Fluorescence in Situ Hybridization Conventional cytogenetics can be applied only to cells that can be induced into mitosis. This can be a severe limiting factor, especially in the study ofsolid tumors.Fluoresce...
25. Knowledge on egg and juvenile development forI. coindetiiis limited11, and egg masses have never been observed in situ except by Naef2who reported«floating devices»from the Mediterranean Sea, together with his drawings of juvenile squid, later thought to beI. coindetii26. However, ...
High-definition spatial transcriptomics for in situ tissue profiling. Nat Methods. 2019;16(10):987–90. CAS PubMed PubMed Central Google Scholar Stickels RR, Murray E, Kumar P, Li J, Marshall JL, Di Bella DJ, et al. Highly sensitive spatial transcriptomics at near-cellular resolution with...
Biology of Stem Cells in Human Umbilical Cord Stroma: In Situ and In Vitro SurveysHumanUmbilical cordMesenchymal stem cellsDifferentiationCytoskeletonCells in the umbilical cord stroma have gained attention in recent years; however, differentiation to certain lineages in humans has been demonstrated in ...
Nevertheless, in situ data reveal that detection of toxins in SPATT by LC-MS is no earlier than their detection in shellfish when LC-MS is the method used for toxin monitoring. In addition, toxins remain in the water column and are adsorbed by the SPATT long after Dinophysis cells are ...
The interspin distances are measured in situ, using pulsed electron–electron double resonance (PELDOR or DEER) spectroscopy. The residual background signals, which are problematic for in situ structural biology, contribute specifically to the intermolecular part of the signal and can be selectively ...