During mitosis one parent cell divides to create two, identical daughter cells. Why are they called daughter cells? The resulting cells from mitosis are called daughter cells because they are the product of a parent cell dividing, much like a parent organism also can make daughters....
We observe the generation of abnormal structures of the nucleus that arise as a consequence of errors in mitosis, including micronuclei and chromosome bridges, and determine their contribution to common karyotype aberrations including whole chromosome loss that has been recently reported after editing in...
Renal tubular epithelial cells (RTECs) stand as among the most critical cells in the renal parenchyma, significantly influencing the physiological functions of the kidneys. These cells are characterized by their abundant mitochondria, signifying their high metabolic and energy demands. Situated in areas ...
The continuous release of growth signals within tumor cells promotes the cell cycle process and induces mitosis. Activation of oncogenes and inactivation of tumor suppressor genes accelerate cell cycle progression by regulating the distribution of growth signals. In a wide range of tumors, METTL3 ...
DS studies in human patients are limited for obvious ethical reasons, resulting in the use of differential models that have been proposed to study this syndrome. Mouse models or induced pluripotent stem cells (iPSCs) cells are a few examples of the strategies developed so far to provide new ...
The liver is unique in its ability to regenerate from a wide range of injuries and diseases. Liver regeneration centers around hepatocyte proliferation and requires the coordinated actions of nonparenchymal cells, including biliary epithelial cells, live
At this stage of mitosis (cytokinesis) the size difference of the neuroblast and GMC nuclei is not as pronounced as in the interphase since the nuclei have not reached their final dimension. The brackets on top of the GMC and below the neuroblast (nb) indicate the diameter size of the ...
T lymphocytesare part of the multi-lineagehematopoietic systememerging fromhematopoietic stem cells(HSCs). The central role ofT cellsinadaptive immunityis highlighted bygeneticdefects that abrogate T-cell development, which causessevere combined immunodeficiency[1]. SCID is lethal within the first two yea...
In contrast, the generative cell undergoes a second mitosis to generate two sperm cells that progress through S-phase prior to double fertilization, when RdDM pathways are transiently switched off12,17. For this reason, epigenetic reprogramming in the male germline has been largely associated to ...
Regeneration often involves the formation of a blastema, an outgrowth or regenerative bud formed at the plane of injury where missing tissues are produced. The mechanisms that trigger blastema formation are therefore fundamental for regeneration. Here, w