The ATP synthase is involved in generating mitochondrial cristae morphology. The EMBO Journal. 2002; 21 :221–230. doi: 10.1093/emboj/21.3.221. [ Cross Ref ]Paumard P , Vaillier J , Coulary B , Schaeffer J , Soubannier V , Mueller DM , Brèthes D , di Rago J...
Various intracellular bacteria depend on host mitochondrial function to parasitize energy and nutrients stores29. Chlamydiae, for instance, lack an F1-F0 ATP synthase for H+-driven ATP synthesis30 as well as genes for the biosynthesis of vitamins, purines, pyrimidines, and almost all amino acids...
ATP synthase contains a highly regulated, multi-conductance channel that is contained within the c-subunit ring of the main membrane bound (FO) portion (Alavian et al., 2014; Mnatsakanyan et al., 2019). Pathological opening of the channel may occur upon conformational change of the ATP synt...
The transsulfuration pathway (TSP) is an evolutionarily conserved pathway that commits methionine to cysteine synthesis in metazoan1,2,3. There are two key enzymes, cystathionine β-synthase (CBS) and cystathionase (CTH, also called cystathionine γ-lyase, GCL), in this pathway. CBS converts ...
F1Fo-ATP synthase consists of the membrane-embedded Fo subcomplex with, in most bacteria, a subunit composition of ab2c10, and the peripheral F1 subcomplex, with a subunit composition of α3β3γδϵ. The energy necessary for ATP synthesis is derived from an electrochemical transmembrane ...
Since C. sticklandii possesses both pathways, a possible function of the Wood-Ljungdahl pathway may be the formation of methylene-THF from CO2, which is then used in the glycine synthase/glycine reductase pathway as described for amino acid-fermenting "acetogenic" bacteria. However, this does ...
The cell wall of Gram-positive bacteria is a complex assemblage of glycopolymers and proteins. It consists of a thick peptidoglycan sacculus that surrounds the cytoplasmic membrane and that is decorated with teichoic acids, polysaccharides, and proteins.
protomer in the L conformation.(对,O conformation is not the binding stage,L conformation is the binding stage,ADP+Pi=ATP+H2O)C. ATP binds to the protomer in the O conformation (错,ATP does not bind in O conformation)D. ATP synthase is not an enzyme droved by ...
Dean M, Rzhetsky A, Allikmets R: The human ATP-binding cassette (ABC) transporter superfamily. Genome Res. 2001, 11: 1156-1166. Article CAS PubMed Google Scholar Holland IB, Cole SPC, Kuchler K, Higgins CF: ABC proteins: from bacteria to man. 2003, Academic press: London Uk Google...
Ca. T. diatomicola has a strongly reduced genome size, but the genome still encodes core carbon-processing pathways such as glycolysis and the tricarboxylic acid (TCA) cycle, which are present in many heterotrophic bacteria. However, on the basis of the low transcription of glycolysis genes (Su...