On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models. Nature 539, 107–111 (2016). Article CAS PubMed PubMed Central Google Scholar Gordan, J. D. et al. HIF-α effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma. ...
1e)3. However, the ammonolysis reaction involves the dissociation of NH3–N2 and H2 (Fig. 3a) and thus provides a highly reducing atmosphere, which gives a certain constraint on available metals. To increase the reactivity of ammonia, a microwave oven is used to generate an ammonia plasma2...
In the following reaction, in which direction will the position of the equilibrium be shifted when in a rigid reaction container, some Ar(g) is added? 2HI(g) gives H2(g) + I2(g) In the following reaction, in which direction w...
This method could be improved by carrying out under pressure depending on the chemical nature of essential oil [21]. 2.1.1.2.1. Advantages of Direct Steam Distillation 2.1.1.2.2. Disadvantage of Direct Steam Distillation 2.1.1.3. Solvent extraction A hydrocarbon solvent is added to the plant ...
The red curves ina,bshow pudding-mold band structure in CuAlO2[46] and BaPdS2[54], respectively. Schematic figure of the electronic structure within the pudding-mold structure shown in (c) and compare to the one of a typical metal (d). Moreover,e,frepresent the band dispersion [55]. ...
The induced conformational changes are detectable in the form of a chemical shift separation between two NMR active 13C labels in 13C-labelled foldamer 27*. Hydrogen sulfide (HS−), as the prevalent conjugate-base form of H2S at physiological pH, has emerged as a crucial biomolecule in ...
This paper addresses the study of a pillow lava interbedded with Late Albian-Early Cenomanian sediments that crops out in Armintza (Bizkaia, Northern Spain
In which direction will the following equilibrium reaction shift in order to reestablish equilibrium if the temperature is increased? A(g) + 2B(aq) arrow 2C(g); Delta Hrxn = 25 kJ Given the following reaction: heat + CaCO3(s) ...
Zygotic genome activation (ZGA) marks the beginning of the embryonic program for a totipotent embryo, which gives rise to the inner cell mass (ICM) where pluripotent epiblast arises, and extraembryonic trophectoderm. However, how ZGA is connected to the first lineage segregation in mammalian embryos...
Stereotyped behaviors are series of postures that show very little variability between repeats. They have been used to classify the dynamics of individuals, groups and species without reference to the lower-level mechanisms that drive them. Stereotypes a