Muscle glutamate is a central amino acid for all transamination reactions that integrate with the TCA cycle. However, at the onset of exercise muscle glutamate decreases despite a constant uptake from the circulation. This thesis investigated whether: (1) glutamate affects metabolic homeostasis in ...
The results of more recent studies, however, are consistent with the idea that expansion of the muscle TCA intermediate pool is principally a reflection of muscle pyruvate availability, and is of little functional importance to TCA cycle... D Constantin-Teodosiu,PL Greenhaff - 《Current Opinion...
About forty years ago, the first use of granular biomass in biotechnological applications was described10. From a bioprocess perspective, the high settleability of granules facilitates the recovery and reuse of the active microbial biomass. In biotechnological applications, for example in upflow anaerobic...
surrounding somatic cells, and the follicular fluid (FF) that is derived from both circulating and intrafollicular derived factors5,6,7,8,9,10,11,12,13,14. The mid-cycle surge of luteinizing hormone (LH), the master regulator of ovulation...
cruzi [5]. However, there are multiple reports of T. cruzi transmission involving secondary or non-domestic adventitious household-invading triatomines, such as R. pallescens, Eratyrus cuspidatus, T. venosa and T. maculata; which suggest the importance of the sylvatic cycle and a close ...
TCA cycleMetabolomic technologies including imaging mass spectrometry (IMS; also called mass spectrometry imaging, MSI, or matrix-assisted laser desorption/ionization-mass spectrometry imaging, MALDI MSI) are important methods to evaluate levels of many compounds in brain with high spatial resolution, ...
The sequences of the primers used were a 5-cgttagatctcagcttcaacaatttctccgg-3' (forward) and 5'-ccggagaaattgttgaagctgagatctaacg-3' (reverse). All of the resulting plasmids were fully sequenced to confirm the presence of the intended changes and the absence of other alterations. After ...
Increased C-acceptor demand for amino acid synthesis, resulting from elevated levels of N in seeds, initiates sucrose mobilization and sucrose-dependent pathways via sucrose synthase, glycolysis and the TCA cycle. The AAP1 seeds display a limitation in C, which leads to the catabolism of arginine...
After blocking transamination with AOAA, metabolism of glutamate through the TCA cycle was still taking place since lactate labeling was only slightly reduced. Glutamate and glutamine synthesis from 2-oxoglutarate could, however, not be detected under this condition. It therefore appears that while ...
Hence, Ca2+ released from the ER is "quasi-synaptically" transferred to mitochondrial matrix, where Ca2+ stimulates mitochondrial ATP synthesis by activating the tricarboxylic acid (TCA) cycle. However, when the Ca2+ transfer is excessive and sustained, mitochondrial Ca2+ overload induces apoptosis ...